Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

Fatty acids are essential for survival, acting as bioenergetic substrates, structural
components and signalling molecules. Given their vital role, cells have evolved mechanisms …

Is there a role for AMPK in the control of hepatic gluconeogenesis and could targeting AMPK
in liver be a viable strategy for treating type 2 diabetes? These are frequently asked …

Objective The goal of this study was to determine the presence early of markers of
endoplasmic reticulum stress (ERS) and insulin resistance in the offspring from dams fed …

Fatty acid metabolism is implicated in the hypothalamic control of food intake. In this regard,
malonyl-CoA, an intermediate in fatty acid synthesis, is emerging as a key player. Malonyl …

Background In response to energy abundant or deprived conditions, nutrients and
hormones activate hypothalamic pathways to maintain energy and glucose homeostasis …

Objective The purpose of this study is to investigate the anti-diabetic effects of linarin, a
flavonoid extracted from Chrysanthemi Indici Flos (CIF), and its potential mechanisms …

Eating behavior is regulated by central and peripheral signals, which interact to modulate
the response to nutrient intake. Central control is mediated by the hypothalamus through …

It is known that biotin prevents the development of diabetes by increasing the functions of
pancreatic beta-cells and improving insulin sensitivity in the periphery. However, its anti …

Objectives This study is designed to evaluate the role of tuberoinfundibular peptide of 39
(TIP39) in connection with glucocorticoid receptor-mediated glutamate/GABA abnormalities …