Inhibiting cell survival and inducing cell death are the main approaches of tumor therapy.
Autophagy plays an important role on intracellular metabolic homeostasis by eliminating …

Autophagy and apoptosis are two crucial self-destructive processes that maintain cellular
homeostasis, which are characterized by their morphology and regulated through signal …

Ferroptosis is a regulated form of cell death driven by small molecules or conditions that
induce lipid-based reactive oxygen species (ROS) accumulation. This form of iron …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

MicroRNAs (miRNAs) are endogenous 22 nt non-coding RNAs that target mRNAs for
cleavage or translational repression. Numerous miRNAs regulate programmed cell death …

Autophagy is a conserved process by which cytoplasmic components are degraded by the
lysosome. It is commonly seen as a cytoplasmic event and, until now, nuclear events were …

Autophagy has emerged as a critical lysosomal pathway that maintains cell function and
survival through the degradation of cellular components such as organelles and proteins …

Macroautophagy is a major intracellular degradation process recognized as playing a
central role in cell survival and longevity. This multistep process is extensively regulated at …

Macroautophagy (hereafter autophagy), literally defined as a type of self-eating, is a
dynamic cellular process in which cytoplasm is sequestered within a unique compartment …

Autophagy is a tightly-regulated catabolic process of cellular self-digestion by which cellular
components are targeted to lysosomes for their degradation. Key functions of autophagy are …