Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated cancer risk

RV Hewavisenti, J Arena, CL Ahlenstiel… - Frontiers in …, 2023 - frontiersin.org
Human papillomavirus (HPV), a common sexually transmitted virus infecting mucosal or
cutaneous stratified epithelia, is implicated in the rising of associated cancers worldwide …

Role of immunity and vaginal microbiome in clearance and persistence of human papillomavirus infection

L Ntuli, A Mtshali, G Mzobe, LJP Liebenberg… - Frontiers in cellular …, 2022 - frontiersin.org
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

Sensitive and amplification-free electrochemiluminescence biosensor for HPV-16 detection based on CRISPR/Cas12a and DNA tetrahedron nanostructures

L Yu, Y Peng, M Sheng, Q Wang, J Huang, X Yang - ACS sensors, 2023 - ACS Publications
Rapid and accurate detection of biomarkers was very important for early screening and
treatment of diseases. Herein, a sensitive and amplification-free electrochemiluminescence …

PCN-224/nano-zinc oxide nanocomposite-based electrochemiluminescence biosensor for HPV-16 detection by multiple cycling amplification and hybridization chain …

D Wu, W Dong, T Yin, G Jie, H Zhou - Sensors and Actuators B: Chemical, 2022 - Elsevier
A new electrochemiluminescence (ECL) biosensing platform using PCN-224/nano-zinc
oxide composites coupled with cyclic amplification and hybridization chain reaction (HCR) …

HPV and the Risk of HIV Acquisition in Women

R Zayats, TT Murooka, LR McKinnon - Frontiers in cellular and …, 2022 - frontiersin.org
The risk of HIV acquisition is low on a per-contact basis but increased by transmission co-
factors such as other sexually transmitted infections (STIs). Human papillomavirus (HPV) is a …

High-risk human papillomavirus prevalence among South African women diagnosed with other STIs and BV

W Qulu, A Mtshali, F Osman, N Ndlela, L Ntuli… - Plos one, 2023 - journals.plos.org
Introduction Human papillomavirus (HPV) infection is a leading cause of cervical cancer.
Although this relies on infection and persistence of HPV in epithelial cells, often occurring in …

The vaginal virome—balancing female genital tract bacteriome, mucosal immunity, and sexual and reproductive health outcomes?

AU Happel, A Varsani, C Balle, JA Passmore… - Viruses, 2020 - mdpi.com
Besides bacteria, fungi, protists and archaea, the vaginal ecosystem also contains a range
of prokaryote-and eukaryote-infecting viruses, which are collectively referred to as the …

Genetic predisposition to persistent human papillomavirus-infection and virus-induced cancers

H Espinoza, KT Ha, TT Pham, JL Espinoza - Microorganisms, 2021 - mdpi.com
Human papillomaviruses (HPVs) are the most common sexually transmitted pathogens
worldwide and among the more than 200 identified HPV types, approximately 15 high risk …

Non-Lactobacillus-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of …

Y Wang, L Noël-Romas, M Perner… - Clinical Infectious …, 2023 - academic.oup.com
Background Adolescent girls and young women aged 15‒24 years in sub-Saharan Africa
are at disproportionate risk of human immunodeficiency virus (HIV) infection. Given the …

The penis, the vagina and HIV risk: key differences (aside from the obvious)

R Kaul, CM Liu, DE Park, RM Galiwango, AAR Tobian… - Viruses, 2022 - mdpi.com
Globally, most Human Immunodeficiency Virus type 1 (HIV) transmission occurs through
vaginal–penile sex (heterosexual transmission). The local immune environment at the site of …