Vaccines for visceral leishmaniasis: A review

K Jain, NK Jain - Journal of immunological methods, 2015 - Elsevier
Visceral leishmaniasis, which is also known as Kala-Azar, is one of the most severely
neglected tropical diseases recognized by the World Health Organization (WHO). The threat …

Vaccines to prevent leishmaniasis

R Kumar, C Engwerda - Clinical & translational immunology, 2014 - Wiley Online Library
Leishmaniasis is a parasitic disease that encompasses a range of clinical manifestations
affecting people in tropical and subtropical regions of the world. Epidemiological and …

Chemotherapeutics of visceral leishmaniasis: present and future developments

S Sundar, A Singh - Parasitology, 2018 - cambridge.org
Treatment of Visceral Leishmaniasis (VL), a neglected tropical disease, is very challenging
with few treatment options. Long duration of treatment and drug toxicity further limit the target …

Recent developments and future prospects in the treatment of visceral leishmaniasis

S Sundar, A Singh - Therapeutic advances in infectious …, 2016 - journals.sagepub.com
Limited therapeutic options in visceral leishmaniasis (VL) make the treatment of this
neglected disease very challenging. In addition to this, long treatment duration and toxic …

From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH‐F3+ GLA‐SE

RN Coler, MS Duthie, KA Hofmeyer… - Clinical & …, 2015 - Wiley Online Library
Key antigens of Leishmania species identified in the context of host responses in
Leishmania‐exposed individuals from disease‐endemic areas were prioritized for the …

Vaccine candidates for leishmaniasis: a review

R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …

Leish-111f, a Recombinant Polyprotein Vaccine That Protects against Visceral Leishmaniasis by Elicitation of CD4+ T Cells

RN Coler, Y Goto, L Bogatzki, V Raman… - Infection and …, 2007 - Am Soc Microbiol
The Leishmania-derived recombinant polyprotein Leish-111f or its three component
proteins, thiol-specific antioxidant (TSA), Leishmania major stress-inducible protein 1 …

[HTML][HTML] Vaccination in leishmaniasis: a review article

L Abdellahi, F Iraji, A Mahmoudabadi… - Iranian Biomedical …, 2022 - ncbi.nlm.nih.gov
Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through
female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics …

Case study for a vaccine against leishmaniasis

J Alvar, SL Croft, P Kaye, A Khamesipour, S Sundar… - Vaccine, 2013 - Elsevier
Leishmaniasis in many ways offers a unique vaccine case study. Two reasons for this are
that leishmaniasis is a disease complex caused by several different species of parasite that …

The development and clinical evaluation of second-generation leishmaniasis vaccines

MS Duthie, VS Raman, FM Piazza, SG Reed - Vaccine, 2012 - Elsevier
Infection with Leishmania parasites results in a range of clinical manifestations and
outcomes. Control of Leishmania parasite transmission is extremely difficult due to the large …