Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

S Bindu, S Mazumder, U Bandyopadhyay - Biochemical pharmacology, 2020 - Elsevier
Owing to the efficacy in reducing pain and inflammation, non-steroidal anti-inflammatory
drugs (NSAIDs) are amongst the most popularly used medicines confirming their position in …

Mechanisms of damage to the gastrointestinal tract from nonsteroidal anti-inflammatory drugs

I Bjarnason, C Scarpignato, E Holmgren, M Olszewski… - Gastroenterology, 2018 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) can damage the gastrointestinal tract,
causing widespread morbidity and mortality. Although mechanisms of damage involve the …

Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal …

M Pennazio, C Spada, R Eliakim, M Keuchel… - …, 2015 - thieme-connect.com
This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy
(ESGE). The Guideline was also reviewed and endorsed by the British Society of …

European evidence based consensus for endoscopy in inflammatory bowel disease

V Annese, M Daperno, MD Rutter… - Journal of Crohn's …, 2013 - academic.oup.com
Endoscopy plays an essential role in the diagnosis, management, prognosis, and
surveillance of inflammatory bowel disease (IBD), but surprisingly there are few available …

Nonsteroidal anti-inflammatory drugs and upper and lower gastrointestinal mucosal damage

C Sostres, CJ Gargallo, A Lanas - Arthritis research & therapy, 2013 - Springer
NSAIDs are among the most commonly used drugs worldwide and their beneficial
therapeutic properties are thoroughly accepted. However, they are also associated with …

NSAID–gut microbiota interactions

D Maseda, E Ricciotti - Frontiers in pharmacology, 2020 - frontiersin.org
Nonsteroidal anti-inflammatory drugs (NSAID) s relieve pain, inflammation, and fever by
inhibiting the activity of cyclooxygenase isozymes (COX-1 and COX-2). Despite their clinical …

Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis

JL Wallace, S Syer, E Denou, G de Palma, L Vong… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Proton pump inhibitors (PPIs) and nonsteroidal anti-inflammatory
drugs (NSAIDs) are among the most commonly used classes of drugs, with the former …

Fecal calprotectin

RM Ayling, K Kok - Advances in clinical chemistry, 2018 - Elsevier
Calprotectin is a 36 kDa member of the S100 family of proteins. It is derived predominantly
from neutrophils and has direct antimicrobial effects and a role within the innate immune …

Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis–an expert consensus addressing benefits as well as gastrointestinal and …

C Scarpignato, A Lanas, C Blandizzi, WF Lems… - BMC medicine, 2015 - Springer
Background There are several guidelines addressing the issues around the use of NSAIDs.
However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk …

[HTML][HTML] Differential diagnosis in inflammatory bowel disease colitis: state of the art and future perspectives

GE Tontini, M Vecchi, L Pastorelli… - World journal of …, 2015 - ncbi.nlm.nih.gov
Distinction between Crohn's disease of the colon-rectum and ulcerative colitis or
inflammatory bowel disease (IBD) type unclassified can be of pivotal importance for a …