Lipolysis: cellular mechanisms for lipid mobilization from fat stores
The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics
In mammals, the white adipocyte is a cell type that is specialized for storage of energy (in the
form of triacylglycerols) and for energy mobilization (as fatty acids). White adipocyte …
form of triacylglycerols) and for energy mobilization (as fatty acids). White adipocyte …
Commensal Cutibacterium acnes induce epidermal lipid synthesis important for skin barrier function
Lipid synthesis is necessary for formation of epithelial barriers and homeostasis with
external microbes. An analysis of the response of human keratinocytes to several different …
external microbes. An analysis of the response of human keratinocytes to several different …
Adipocyte regulation of insulin sensitivity and the risk of type 2 diabetes
A Santoro, BB Kahn - New England Journal of Medicine, 2023 - Mass Medical Soc
Adipocyte Regulation of Insulin Sensitivity and the Risk of Type 2 Diabetes | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Lipid droplets and liver disease: from basic biology to clinical implications
NL Gluchowski, M Becuwe, TC Walther… - Nature reviews …, 2017 - nature.com
Lipid droplets are dynamic organelles that store neutral lipids during times of energy excess
and serve as an energy reservoir during deprivation. Many prevalent metabolic diseases …
and serve as an energy reservoir during deprivation. Many prevalent metabolic diseases …
Cytosolic lipolysis and lipophagy: two sides of the same coin
Fatty acids are the most efficient substrates for energy production in vertebrates and are
essential components of the lipids that form biological membranes. Synthesis of …
essential components of the lipids that form biological membranes. Synthesis of …
The regulation of fat metabolism during aerobic exercise
A Muscella, E Stefàno, P Lunetti, L Capobianco… - Biomolecules, 2020 - mdpi.com
Since the lipid profile is altered by physical activity, the study of lipid metabolism is a
remarkable element in understanding if and how physical activity affects the health of both …
remarkable element in understanding if and how physical activity affects the health of both …
Regulation of glucose and lipid metabolism in health and disease
Glucose and fatty acids are the major sources of energy for human body. Cholesterol, the
most abundant sterol in mammals, is a key component of cell membranes although it does …
most abundant sterol in mammals, is a key component of cell membranes although it does …
Cardiomyopathy in obesity, insulin resistance and diabetes
M Nakamura, J Sadoshima - The Journal of physiology, 2020 - Wiley Online Library
The prevalence of obesity, insulin resistance and diabetes is increasing rapidly. Most
patients with these disorders have hypertriglyceridaemia and increased plasma levels of …
patients with these disorders have hypertriglyceridaemia and increased plasma levels of …
Lipid droplets in health and disease
Lipids are essential building blocks synthesized by complex molecular pathways and
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …