Heat shock proteins (HSPs) constitute a large family of proteins involved in protein folding
and maturation whose expression is induced by heat shock or other stressors. The major …

Extracellular heat shock proteins (ex-HSPs) have been found in exosomes, oncosomes,
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …

Heat shock proteins (hsp) have been found to play a fundamental role in the recovery from
multiple stress conditions and to offer protection from subsequent insults. The function of hsp …

Humans contain many HSP (heat-shock protein) 70/HSPA-and HSP40/DNAJ-encoding
genes and most of the corresponding proteins are localized in the cytosol. To test for …

Few effective therapies exist for the treatment of neurodegenerative diseases that have been
characterized as protein misfolding disorders. Upregulation of heat shock proteins (Hsps) …

Heat shock proteins are involved in cellular repair and protective mechanisms that counter
characteristic features of neurodegenerative diseases such as protein misfolding and …

In the present study, withaferin A (WA), a steroidal lactone with anti-inflammatory and anti-
tumor properties, inhibited proteasome activity and induced endoplasmic reticulum (ER) and …

For many years the perception has been that mammalian stress proteins are intracellular
molecules that are only present in the extracellular environment as a consequence of …

Background The VATER/VACTERL association refers to the nonrandom co‐occurrence of at
least three of the following component features (CFs): vertebral defects (V), anorectal …

Abstract Mutations in the Forkhead Box C1 (FOXC1) transcription factor gene are associated
with Axenfeld-Rieger syndrome (ARS), a developmental disorder affecting structures in the …