Neuropathic pain is a debilitating form of chronic pain resulting from nerve injury, disease
states, or toxic insults. Neuropathic pain is often refractory to conventional …

The cannabinoid receptor type 2 (CB2) is a class A GPCR that was cloned in 1993 while
looking for an alternative receptor that could explain the pharmacological properties of Δ9 …

In recent years, several nations have implemented various measures to control the surge of
new synthetic cannabinoid receptor agonists (SCRAs) entering the recreational drug market …

This review provides detailed methods for the synthesis, structures and chemical properties
of hydrazones bearing carboxamide, thioamide and amidine functions. The main accent was …

To curb the manufacturing, trafficking, and abuse of synthetic cannabinoids, China
implemented a class‐wide regulation on synthetic cannabinoids in July 2021. Recently …

Synthetic cannabinoids (SCs), often sold as “legal” replacements for cannabis, are the
largest group of new psychoactive substances monitored by the European Monitoring …

A series of novel di-or trisubstituted isatin derivatives were designed and synthesized in 5–6
steps in 25–45% overall yields. Their structures were confirmed by 1H NMR and 13C NMR …

In recent years, cell cycle and checkpoint pathways regulation are offering new therapeutic
approaches against cancer. Isatin, is a well exploited scaffold in the anticancer domain …

Background: Since the discovery of cannabinoid receptors and their endogenous ligands in
early 1990s, the endocannabinoid system has been shown to play a vital role in several …

Forty four di-or trisubstituted novel isatin derivatives were designed and synthesized in 5–6
steps in 25–45% overall yields. Their structures were confirmed by 1 H NMR and 13 C NMR …