The final stage of brain development is associated with the generation and maturation of
neuronal synapses. However, the same period is also associated with a peak in synapse …

Adolescence marks a time of unique neurocognitive development, in which executive
functions reach adult levels of maturation. While many core facets of executive function may …

Post-traumatic stress disorder (PTSD) can develop following severe trauma, but the extent to
which genetic and environmental risk factors contribute to individual clinical outcomes is …

The prenatal and early postnatal stages represent a critical time window for human brain
development. Interestingly, this window partly overlaps with the maturation of the intestinal …

A strong association between perinatal viral infections and neurodevelopmental disorders
has been established. Both the direct contact of the virus with the developing brain and the …

Importance Duration of untreated psychosis (DUP) has been associated with poor outcomes
in schizophrenia, but the mechanism responsible for this association is not known …

Developmental neuronal remodeling is an evolutionarily conserved mechanism required for
precise wiring of nervous systems. Despite its fundamental role in neurodevelopment and …

Developmental neuronal remodeling is a crucial step in sculpting the final and mature brain
connectivity in both vertebrates and invertebrates. Remodeling includes degenerative …

During development, neurons switch among growth states, such as initial axon outgrowth,
axon pruning, and regrowth. By studying the stereotypic remodeling of the Drosophila …

Regulation of axon guidance and pruning of inappropriate synapses by class 3
semaphorins are key to the development of neural circuits. Collapsin response mediator …