Methylenetetrahydrofolate reductase (MTHFR) is a critical enzyme of folate pathway and
required for DNA synthesis and methylation. MTHFE C677T polymorphisms is reported as …

Background and Objectives Methylenetetrahydrofolate reductase (MTHFR) polymorphism
may be a risk factor for male infertility. However, the epidemiologic studies showed …

Several studies showed that the genetic mutations in the folate-related enzyme genes might
be associated with male infertility; however, the results were still inconsistent. We performed …

Methylenetetrahydrofolate reductase (MTHFR) functions as a main regulatory enzyme in
folate metabolism. The association of MTHFR gene Ala222Val polymorphism with male …

Background and objectives One of the possible male sterility risk factors are polymorphisms
of Methylenetetrahydrofolate reductase (MTHFR). However, the epidemiologic …

Although published studies have reported the association between MTHFR C677T (rs
1801133), A1298C (rs 1801131), and MTRR A66G (rs1801394) polymorphisms and male …

Male infertility is a multifactorial syndrome encompassing a wide variety of disorders. In
recent years, several genome-wide single-nucleotide polymorphism (SNP) association …

Purpose This study explored the possible association of four single nucleotide
polymorphisms (SNPs) of the three folate-related enzyme genes: MTHFR C677T and …

Published studies on the association between the C677T and A1298C polymorphisms of the
methylenetetrahydrofolate reductase (MTHFR) gene and male infertility risk are …

Background. Congenital heart defect (CHD) is one of the most common birth defects in the
world. The methylenetetrahydrofolate reductase (MTHFR) and methionine synthase …