[HTML][HTML] Immunomodulatory effects of vitamin D in pregnancy and beyond

F Cyprian, E Lefkou, K Varoudi, G Girardi - Frontiers in immunology, 2019 - frontiersin.org
In addition to its role in calcium homeostasis and bone formation, a modulatory role of the
active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been …

Fibrocytes: emerging effector cells in chronic inflammation

RA Reilkoff, R Bucala, EL Herzog - Nature Reviews Immunology, 2011 - nature.com
Fibrocytes are mesenchymal cells that arise from monocyte precursors. They are present in
injured organs and have both the inflammatory features of macrophages and the tissue …

[HTML][HTML] Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation

W Stephenson, LT Donlin, A Butler, C Rozo… - Nature …, 2018 - nature.com
Droplet-based single-cell RNA-seq has emerged as a powerful technique for massively
parallel cellular profiling. While this approach offers the exciting promise to deconvolute …

A multifunctional nano-therapeutic platform based on octahedral yolk-shell Au NR@ CuS: Photothermal/photodynamic and targeted drug delivery tri-combined …

R Huang, C Zhang, Y Bu, Z Li, X Zheng, S Qiu… - Biomaterials, 2021 - Elsevier
Rheumatoid arthritis (RA) is a common chronic autoimmune disease that results from
synovial hyperplasia. The hyperplasia of synovium directly degrades cartilage by secreting …

Rheumatoid arthritis progression mediated by activated synovial fibroblasts

E Neumann, S Lefèvre, B Zimmermann, S Gay… - Trends in molecular …, 2010 - cell.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial
hyperplasia and progressive joint destruction. Rheumatoid arthritis synovial fibroblasts …

[Retracted] Multifunctional Therapeutic Approach of Nanomedicines against Inflammation in Cancer and Aging

MM Rahman, F Islam, S Afsana Mim… - Journal of …, 2022 - Wiley Online Library
Cancer is a fatal disorder that affects people across the globe, yet existing therapeutics are
ineffective. The development of submicrometer transport for optimizing the biodistribution of …

[HTML][HTML] Mesenchymal stem cells improve rheumatoid arthritis progression by controlling memory T cell response

N Luque-Campos, RA Contreras-López… - Frontiers in …, 2019 - frontiersin.org
In the last years, mesenchymal stem cell (MSC)-based therapies have become an
interesting therapeutic opportunity for the treatment of rheumatoid arthritis (RA) due to their …

[HTML][HTML] A novel phytochemical, DIM, inhibits proliferation, migration, invasion and TNF-α induced inflammatory cytokine production of synovial fibroblasts from …

H Du, X Zhang, Y Zeng, X Huang, H Chen… - Frontiers in …, 2019 - frontiersin.org
In rheumatoid arthritis (RA) pathogenesis, activated RA fibroblast-like synoviocytes (RA-
FLSs) exhibit similar proliferative features as tumor cells and subsequent erosion to cartilage …

[HTML][HTML] Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis

SK Drexler, PL Kong, J Wales, BM Foxwell - Arthritis research & therapy, 2008 - Springer
Rheumatoid arthritis is a multisystemic auto-inflammatory disease affecting up to 1% of the
population and leading to the destruction of the joints. Evidence exists for the involvement of …

[HTML][HTML] Cytokines in the pathogenesis of rheumatoid arthritis: new players and therapeutic targets

A Alunno, F Carubbi, R Giacomelli, R Gerli - BMC rheumatology, 2017 - Springer
In recent years, the landscape of pro-and anti-inflammatory cytokines has rapidly expanded
with the identification of new members proven to be involved at different extent in the …