The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …

The last decades have seen a tremendous expanse in the application of C H activation of
many different substrate classes, including the invaluable indole scaffold. Following the …

Functionalized biaryl-containing motifs are among the most valuable synthetic scaffolds in
organic chemistry with wide ranging commercial applications in pharmaceuticals, functional …

Over the last two decades, transition-metal catalyzed C–H functionalization of indoles has
emerged as an area of extensive research and tremendous progress has been made in this …

The mechanochemical, solvent‐free, highly regioselective, rhodium‐catalyzed C− H
methylation of (hetero) arenes is reported. The reaction shows excellent functional‐group …

C4-decorated indoles feature in a plethora of bioactive and functional compounds of
importance to natural product synthesis, material sciences, as well as crop protection and …

The ability of the hemilabile (P, N) MeDalphos ligand to trigger oxidative addition of
iodoarenes to gold has been thoroughly studied. Competition experiments and Hammett …

Alkylation represents an important organic transformation in molecular science to develop
privileged alkylated arenes and heteroarenes. Especially, the direct C–H bond alkylation …

The site-selective functionalization of an indole template offers exciting possibilities for the
derivatization of molecules with useful biological properties. Herein, we report the remote C6 …

Among the known aromatic nitrogen heterocycles, pyrrole represents a privileged aromatic
heterocycle ranging its occurrence in the key component of “pigments of life” to biologically …