Bisphenol A (BPA) and cell signaling pathways

M Murata, JH Kang - Biotechnology advances, 2018 - Elsevier
Abstract Bisphenol A (BPA; 4, 4′-isopropylidenediphenol) is an endocrine disruptor that is
used as a material for the production of phenol resins, polyacrylates, polyesters, epoxy …

A comprehensive review on the carcinogenic potential of bisphenol A: clues and evidence

NG Khan, J Correia, D Adiga, PS Rai… - … Science and Pollution …, 2021 - Springer
Abstract Bisphenol A [BPA;(CH 3) 2 C (C 6 H 4 OH) 2] is a synthetic chemical used as a
precursor material for the manufacturing of plastics and resins. It gained attention due to its …

Bisphenol A and male fertility: Myths and realities

C Castellini, M Totaro, A Parisi, S D'Andrea… - Frontiers in …, 2020 - frontiersin.org
Bisphenol A (BPA) represents the main chemical monomer of epoxy resins and
polycarbonate plastics. The environmental presence of BPA is widespread, and it can easily …

[HTML][HTML] Low dose bisphenol A impairs spermatogenesis by suppressing reproductive hormone production and promoting germ cell apoptosis in adult rats

P Jin, X Wang, F Chang, Y Bai, Y Li… - Journal of biomedical …, 2013 - ncbi.nlm.nih.gov
Bisphenol A (BPA), an estrogenic chemical, has been shown to reduce sperm count;
however, the underlying mechanisms remain unknown. Herein, we show that oral …

In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction

A Barbonetti, C Castellini, N Di Giammarco… - Reproductive …, 2016 - Elsevier
As bisphenol A (BPA) exerts oxidative/pro-apoptotic effects in several cell types, we
explored whether the in vitro exposure to BPA could affect human sperm integrity through …

A mini review of bisphenol A (BPA) effects on cancer-related cellular signaling pathways

S Nomiri, R Hoshyar, C Ambrosino, CR Tyler… - … science and pollution …, 2019 - Springer
Bisphenol A (BPA) is a plasticizer used widely in many industrial products and is now well
established as an endocrine-disrupting chemical (EDC). BPA readily leaches out from these …

Pre-natal exposure of mice to bisphenol A elicits an endometriosis-like phenotype in female offspring

PG Signorile, EP Spugnini, L Mita, P Mellone… - General and …, 2010 - Elsevier
Endometriosis is a chronic gynecological disease characterized by the growth of
endometrial tissue outside the uterine cavity. Exposure to endocrine disruptors during critical …

[HTML][HTML] Bisphenol A induces cell cycle arrest in primary and prostate cancer cells through EGFR/ERK/p53 signaling pathway activation

A Bilancio, P Bontempo, M Di Donato, M Conte… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Bisphenol A (BPA) belongs to the class of chemicals known as endocrine disruptors and has
been also involved in the pathogenesis and progression of endocrine related cancer such …

Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes

H Gong, X Zhang, B Cheng, Y Sun, C Li, T Li, L Zheng… - PloS one, 2013 - journals.plos.org
Bisphenol A (BPA) is a chemical compound widely used in manufacturing plastic products.
Recent epidemiological studies suggest BPA exposure is positively associated with the …

Human meiotic progression and recombination are affected by Bisphenol A exposure during in vitro human oocyte development

MA Brieno-Enriquez, P Robles… - Human …, 2011 - academic.oup.com
Abstract BACKGROUND Bisphenol A (BPA) is a 'weak'endocrine disruptor. The effect of
BPA on human reproduction is controversial but has been related to meiotic anomalies …