[HTML][HTML] Natural and synthetic antioxidants targeting cardiac oxidative stress and redox signaling in cardiometabolic diseases

M Barteková, A Adameová, A Görbe… - Free Radical Biology …, 2021 - Elsevier
Cardiometabolic diseases (CMDs) are metabolic diseases (eg, obesity, diabetes,
atherosclerosis, rare genetic metabolic diseases, etc.) associated with cardiac pathologies …

[HTML][HTML] Pharmacological cardioprotection against ischemia reperfusion injury—the search for a clinical effective therapy

Q Wang, CJ Zuurbier, R Huhn, C Torregroza… - Cells, 2023 - mdpi.com
Pharmacological conditioning aims to protect the heart from myocardial ischemia-
reperfusion injury (IRI). Despite extensive research in this area, today, a significant gap …

Cardiopulmonary bypass and oxidative stress

M Zakkar, G Guida, MS Suleiman… - … medicine and cellular …, 2015 - Wiley Online Library
The development of the cardiopulmonary bypass (CPB) revolutionized cardiac surgery and
contributed immensely to improved patients outcomes. CPB is associated with the activation …

Reactive oxygen species in myocardial reperfusion injury: from physiopathology to therapeutic approaches

V Braunersreuther, V Jaquet - Current pharmaceutical …, 2012 - ingentaconnect.com
Myocardial ischemia is a major cause of morbidity and mortality in the world. Although
restoration of blood flow after prolonged ischemia is essential for cardiomyocytes salvation …

Nitric oxide: a guardian for vascular grafts?

A de Mel, F Murad, AM Seifalian - Chemical reviews, 2011 - ACS Publications
Cardiovascular disease is a major cause of mortality and morbidity. Current research
investigating the roles of nitric oxide (NO) with relevance to the cardiovascular system is an …

[HTML][HTML] Antioxidant cardioprotection against reperfusion injury: potential therapeutic roles of resveratrol and quercetin

R Rodrigo, C Retamal, D Schupper… - Molecules, 2022 - mdpi.com
Ischemia-reperfusion myocardial damage is a paradoxical tissue injury occurring during
percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) patients …

[HTML][HTML] Inflammation and oxidative stress in the context of extracorporeal cardiac and pulmonary support

S Hatami, J Hefler, DH Freed - Frontiers in immunology, 2022 - frontiersin.org
Extracorporeal circulation (ECC) systems, including cardiopulmonary bypass, and
extracorporeal membrane oxygenation have been an irreplaceable part of the …

N-acetylcysteine for the prevention of postoperative atrial fibrillation: a prospective, randomized, placebo-controlled pilot study

M Ozaydin, O Peker, D Erdogan, S Kapan… - European heart …, 2008 - academic.oup.com
Aims Oxidative stress has recently been implicated in the pathophysiology of atrial fibrillation
(AF). The aim of the present study was to evaluate the effects of antioxidant agent N …

Myocardial ischaemia reperfusion injury: the challenge of translating ischaemic and anaesthetic protection from animal models to humans

Z Xia, H Li, MG Irwin - BJA: British Journal of Anaesthesia, 2016 - academic.oup.com
Myocardial ischaemia reperfusion injury is the leading cause of death in patients with
cardiovascular disease. Interventions such as ischaemic pre and postconditioning protect …

Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery

R Hall - Journal of Cardiothoracic and Vascular Anesthesia, 2013 - jcvaonline.com
THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …