In global terms, respiratory viral infection is a major cause of morbidity and mortality. Infancy,
in particular, is a time of increased disease susceptibility and severity. Early-life viral …

Respiratory viral infections are associated with a wide range of acute syndromes and
infectious disease processes in children and adults worldwide. Many viruses are implicated …

Background Otitis media (OM) is amongst the most common childhood diseases and is
associated with multiple microbial pathogens within the middle ear. Global and temporal …

SARS-CoV, human coronavirus NL63 (HCoV-NL63) and HCoV-HKU1 were first described
in 2003, 2004 and 2005 respectively. Nevertheless, discovery of three new human …

Viral respiratory infections are very common and they are frequently eliminated from the
body without any detrimental consequences. Secondary serious bacterial infection has been …

Rationale: Secondary bacterial infection following rhinovirus (RV) infection has been
recognized in chronic obstructive pulmonary disease. Objectives: We sought to understand …

Human rhinovirus (HRV) and coronavirus (HCoV) infections are associated with both upper
respiratory tract illness (“the common cold”) and lower respiratory tract illness (pneumonia) …

BACKGROUND AND OBJECTIVES: Antimicrobials are frequently prescribed for acute
respiratory tract infections (ARTI), although many are viral. We aimed to determine bacterial …

Objectives/Hypothesis Intracellular entry of severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2) depends on the interaction between its spike protein with the cellular …

Objective This systematic review examined the epidemiology of otitis media (OM) in
children< 6 years within 90 developing and newly industrialised countries. Methods …