Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification

C Bergom, JA Bradley, AK Ng, P Samson, C Robinson… - Cardio Oncology, 2021 - jacc.org
Radiation therapy is an important component of cancer therapy for many malignancies. With
improvements in cardiac-sparing techniques, radiation-induced cardiac dysfunction has …

Radiation-induced valvular heart disease

DM Gujral, G Lloyd, S Bhattacharyya - Heart, 2016 - heart.bmj.com
Radiation to the mediastinum is a key component of treatment with curative intent for a range
of cancers including Hodgkin's lymphoma and breast cancer. Exposure to radiation is …

Risk for valvular heart disease after treatment for Hodgkin lymphoma

DJ Cutter, M Schaapveld, SC Darby… - Journal of the …, 2015 - academic.oup.com
Background: Hodgkin lymphoma (HL) survivors are at increased risk for developing valvular
heart disease (VHD). We evaluated the determinants of the risk and the radiation dose …

Current survivorship recommendations for patients with Hodgkin lymphoma: focus on late effects

AK Ng - Blood, The Journal of the American Society of …, 2014 - ashpublications.org
Long-term survivors of Hodgkin lymphoma (HL) are at an increased risk for a range of late
complications, with subsequent malignant neoplasm and cardiovascular disease …

Consequences of ionizing radiation exposure to the cardiovascular system

JWS Jahng, MP Little, HJ No, BW Loo Jr… - Nature Reviews …, 2024 - nature.com
Ionizing radiation is widely used in various industrial and medical applications, resulting in
increased exposure for certain populations. Lessons from radiation accidents and …

Cardiovascular complications of radiotherapy

MS Lee, W Finch, E Mahmud - The American journal of cardiology, 2013 - Elsevier
Chest radiotherapy is routinely used to treat malignancies such as Hodgkin disease and
breast cancer but is commonly associated with a variety of cardiovascular complications …

Radiation and the heart: systematic review of dosimetry and cardiac endpoints

JR Niska, CS Thorpe, SM Allen… - Expert review of …, 2018 - Taylor & Francis
Introduction: Recent trials in radiotherapy have associated heart dose and survival,
inadequately explained by the existing literature for radiation-related late cardiac effects …

Different IMRT solutions vs. 3D-Conformal Radiotherapy in early stage Hodgkin's lymphoma: dosimetric comparison and clinical considerations

C Fiandra, AR Filippi, P Catuzzo, A Botticella… - Radiation …, 2012 - Springer
Abstract Background Radiotherapy in Hodgkin's Lymphoma (HL) is currently evolving with
new attempts to further reduce radiation volumes to the involved-node concept (Involved …

Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: the paradigm of radiotherapy

S Logotheti, A Pavlopoulou, HK Rudsari… - Pharmacology & …, 2024 - Elsevier
Advances in cancer therapeutics have improved patient survival rates. However, cancer
survivors may suffer from adverse events either at the time of therapy or later in life …

Cardiotoxicity of mediastinal radiotherapy

I Ratosa, MI Pantar - Reports of Practical Oncology and …, 2019 - journals.viamedica.pl
Background Radiotherapy-related heart injury is well documented, with no apparent safety
threshold dose. The number of long-term cancer survivors exposed to mediastinal …