Pregnancy offers a window of opportunity to program the future health of both mothers and
offspring. During gestation, women experience a series of physical and metabolic …

Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

OBJECTIVE The objective of this study was to evaluate the effect of maternal hyperglycemia
during pregnancy on cardiometabolic risk in offspring during early childhood. RESEARCH …

There is an epidemic of diabetes in Asia. Type 2 diabetes develops in East Asian patients at
a lower mean body mass index (BMI) compared with those of European descent. At any …

Abstract Purpose of Review This review will focus on the long-term outcomes in offspring
exposed to in utero hyperglycemia and gestational diabetes (GDM), including obesity …

Background Rising prevalence of childhood obesity and type 2 diabetes mellitus (T2DM) is
an emerging public health issue. Objectives To investigate the association of maternal …

Gestational diabetes is the most common medical complication in pregnancy. Historically,
gestational diabetes was considered a pregnancy complication involving treatment of rising …

Highlights•Leveraging health capital, even before conception, promotes resilience and
reduces later dependency on health care.•Biological and epigenetic processes operate …

Gestational diabetes mellitus (GDM) is a common condition with increasing prevalence
worldwide. GDM is associated with an increased risk for maternal and neonatal …

Aims/hypothesis Offspring of mothers with diabetes are at increased risk of metabolic
disorders in later life. Increased offspring BMI is a plausible mediator. We performed a …