[HTML][HTML] Principles for the design of multicellular engineered living systems

O Aydin, AP Passaro, R Raman, SE Spellicy… - APL …, 2022 - pubs.aip.org
Remarkable progress in bioengineering over the past two decades has enabled the
formulation of fundamental design principles for a variety of medical and non-medical …

[HTML][HTML] Multicolor strategies for investigating clonal expansion and tissue plasticity

L Dumas, S Clavreul, F Michon, K Loulier - Cellular and Molecular Life …, 2022 - Springer
Understanding the generation of complexity in living organisms requires the use of lineage
tracing tools at a multicellular scale. In this review, we describe the different multicolor …

[HTML][HTML] The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis

NS Michki, Y Li, K Sanjasaz, Y Zhao, FY Shen… - Cell reports, 2021 - cell.com
The Drosophila type II neuroblast lineages present an attractive model to investigate the
neurogenesis and differentiation process as they adapt to a process similar to that in the …

[HTML][HTML] Blind demixing methods for recovering dense neuronal morphology from barcode imaging data

S Chen, J Loper, P Zhou, L Paninski - PLoS Computational …, 2022 - journals.plos.org
Cellular barcoding methods offer the exciting possibility of 'infinite-pseudocolor'anatomical
reconstruction—ie, assigning each neuron its own random unique barcoded …

Unsupervised neural tracing in densely labeled multispectral brainbow images

B Duan, LA Walker, DH Roossien… - 2021 IEEE 18th …, 2021 - ieeexplore.ieee.org
Recent advances in imaging technologies for generating large quantities of high-resolution
3D images, especially multispectral labeling technology such as Brainbow, permits …

nGauge: Integrated and Extensible Neuron Morphology Analysis in Python

LA Walker, JS Williams, Y Li, DH Roossien, WJ Lee… - Neuroinformatics, 2022 - Springer
The study of neuron morphology requires robust and comprehensive methods to quantify
the differences between neurons of different subtypes and animal species. Several software …

Expansion Sequencing of RNA Barcoded Neurons in the Mammalian Brain: Progress and Implications for Molecularly Annotated Connectomics

DR Goodwin, A Vaughan, D Leible, S Alon, GL Henry… - bioRxiv, 2022 - biorxiv.org
Mapping and molecularly annotating mammalian neural circuits is challenging due to the
inability to uniquely label cells while also resolving subcellular features such as synaptic …

Improved blind demixing methods for recovering dense neuronal morphology from barcode imaging data

S Chen, J Loper, P Zhou, L Paninski - bioRxiv, 2021 - biorxiv.org
Cellular barcoding methods offer the exciting possibility of 'infinite-pseudocolor'anatomical
reconstruction—ie, assigning each neuron its own random unique barcoded …

[HTML][HTML] Biotecnología moderna en Latinoamérica: retos y oportunidades

E Moreta, C Oña - catalisisec.com
Uno de los retos más grandes que tiene la neurobiología es el estudio de la gran variedad
de tipos y subtipos de neuronas, así como las conexiones complejas que forman entre ellas …

A multi-informatic description of neural differentiation in the Drosophila type-II neuroblast lineages

NS Michki, Y Li, K Sanjasaz, Y Zhao, FY Shen… - bioRxiv, 2020 - biorxiv.org
To adopt terminal neural fates, neural progenitors respond to a combination of molecular
factors, the interplay between which remains difficult to untangle. In this work, we …