Among the defining features of the animal kingdom is the ability of cells to change shape
and move. This underlies embryonic and postembryonic development, tissue homeostasis …

Mechanotransduction at cell–cell adhesions is crucial for the structural integrity,
organization, and morphogenesis of epithelia. At cell–cell junctions, ternary E-cadherin/β …

α-Catenin couples the cadherin–catenin complex to the actin cytoskeleton. The
mechanosensitive α-Catenin M region undergoes conformational changes upon application …

Cell-cell and cell-matrix junctions transmit mechanical forces during tissue morphogenesis
and homeostasis. α-Catenin links cell-cell adhesion complexes to the actin cytoskeleton …

Attachment between cells is crucial for almost all aspects of the life of cells. These inter-cell
adhesions are mediated by the binding of transmembrane cadherin receptors of one cell to …

细胞膜是细胞与外部环境进行物质与能量交换的界面, 是调节细胞正常生命活动的重要结构基础
. 细胞膜上力敏感受体可通过力学作用方式参与并影响细胞的力信号转导等功能 …

The regulation of cell–cell junctions during epidermal morphogenesis ensures tissue
integrity, a process regulated by α-catenin. This cytoskeletal protein connects the cadherin …

Classical cadherins are transmembrane proteins whose extracellular domains link
neighboring cells, and whose intracellular domains connect to the actin cytoskeleton via β …

As the core component of the adherens junction in cell–cell adhesion, the cadherin–catenin
complex transduces mechanical tension between neighboring cells. Structural studies have …

A hallmark of gastrulation is the establishment of germ layers by internalization of cells
initially on the exterior. In C. elegans the end of gastrulation is marked by the closure of the …