The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …

Cardiovascular diseases (CVD) are complex entities with heterogenous pathophysiologic
mechanisms and increased oxidative stress has been viewed as one of the potential …

Abstract Evaluation of coronary artery disease (CAD) using coronary computed tomography
angiography (CCTA) has seen a paradigm shift in the last decade. Evidence increasingly …

Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Cartilage lesions and osteoarthritis (OA) presents an ever-increasing clinical and
socioeconomic burden. Synovial inflammation and articular inflammatory environment are …

The role of lipids is essential in any phase of the atherosclerotic process, which is
considered a chronic lipid-related and inflammatory condition. The traditional lipid profile …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of
lipids, smooth muscle cell proliferation, cell apoptosis, necrosis, fibrosis, and local …

Emerging data have demonstrated a strong association between the gut microbiota and the
development of cardiovascular disease (CVD) risk factors such as atherosclerosis …

Vascular calcification is a hallmark of atherosclerosis. The location, density, and confluence
of calcification may change portions of the arterial conduit to a noncompliant structure …

Improvements in health care and lifestyle have led to an elevated lifespan and increased
focus on age-associated diseases, such as neurodegeneration, cardiovascular disease …