[HTML][HTML] Plant-derived compounds in treatment of leishmaniasis

A Oryan - Iranian journal of veterinary research, 2015 - ncbi.nlm.nih.gov
Leishmaniasis is a neglected public health problem caused by the protozoan species
belonging to the genus Leishmania affecting mostly the poor populations of developing …

Emerging therapeutic targets for treatment of leishmaniasis

S Sundar, B Singh - Expert opinion on therapeutic targets, 2018 - Taylor & Francis
Introduction: Parasitic diseases that pose a threat to human life include leishmaniasis–
caused by protozoan parasite Leishmania species. Existing drugs have limitations due to …

Flavonoids as efficient scaffolds: Recent trends for malaria, leishmaniasis, Chagas disease, and dengue

PK Boniface, EI Ferreira - Phytotherapy Research, 2019 - Wiley Online Library
Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually with over 500,000 deaths. Among the NTDs, some of the …

Antileishmanial activity and cytotoxicity of Brazilian plants

TG Ribeiro, MA Chávez-Fumagalli, DG Valadares… - Experimental …, 2014 - Elsevier
Leishmaniasis is a major public health problem, and the alarming spread of parasite
resistance has increased the importance of discovering new therapeutic products. The …

[HTML][HTML] Vernonia brasiliana (L.) Druce induces ultrastructural changes and apoptosis-like death of Leishmania infantum promastigotes

R Mondêgo-Oliveira, JC de Sá Sousa… - Biomedicine & …, 2021 - Elsevier
The present study aimed to evaluate the antileishmanial effect, the mechanisms of action
and the association with miltefosine of Vernonia brasiliana essential oil against Leishmania …

Review on natural products as an alternative to contemporary anti-leishmanial therapeutics

S Raj, S Sasidharan, SN Balaji, VK Dubey… - Journal of Proteins and …, 2020 - Springer
Leishmaniasis is a vector-borne protozoan disease caused by an intracellular parasite
which globally affects 350 million people. This infectious disease mainly affects …

Plants used by the rural community of Bananal, Mato Grosso, Brazil: Aspects of popular knowledge

GS Miguéis, RH da Silva, GA Damasceno Junior… - PloS one, 2019 - journals.plos.org
Studies in rural communities are important to maintain popular knowledge between
generations, as well as to identify new species for pharmaceutical production. Thus, the …

Treatment of murine visceral leishmaniasis using an 8-hydroxyquinoline-containing polymeric micelle system

MC Duarte, LM dos Reis Lage, DP Lage… - Parasitology …, 2016 - Elsevier
New therapeutics are urgently needed to treat visceral leishmaniasis (VL). Due to the fact
that drug discovery is a long and expensive process, the development of delivery systems to …

[HTML][HTML] Anti-Leishmanial Activity of Artemisia persica, A. spicigera, and A. fragrance against Leishmania major

M Najm, R Hadighi, M Heidari-Kharaji… - Iranian journal of …, 2021 - ncbi.nlm.nih.gov
Background: Neglected tropical diseases (NTDs) like zoonotic cutaneous leishmaniasis
(ZCL), is a widespread infectious disease with high mortality and morbidity. Various …

Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum

PS Lage, MA Chávez-Fumagalli, JT Mesquita… - Parasitology …, 2015 - Springer
The present study aimed to investigate the in vitro antileishmanial activity of
strychnobiflavone flavonoid against Leishmania infantum, as well as its mechanism of …