[HTML][HTML] Mechanisms of macular edema: beyond the surface

A Daruich, A Matet, A Moulin, L Kowalczuk… - Progress in retinal and …, 2018 - Elsevier
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions

I Klaassen, CJF Van Noorden… - Progress in retinal and …, 2013 - Elsevier
Breakdown of the inner endothelial blood-retinal barrier (BRB), as occurs in diabetic
retinopathy, age-related macular degeneration, retinal vein occlusions, uveitis and other …

New functions of Müller cells

A Reichenbach, A Bringmann - Glia, 2013 - Wiley Online Library
Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …

Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases

N Cuenca, L Fernández-Sánchez, L Campello… - Progress in retinal and …, 2014 - Elsevier
Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives

R Simo, C Hernández - Trends in Endocrinology & Metabolism, 2014 - cell.com
Diabetic retinopathy (DR), one of the leading causes of preventable blindness, has been
considered a microcirculatory disease of the retina. However, there is emerging evidence to …

Retinal macroglial responses in health and disease

R de Hoz, B Rojas, AI Ramírez… - BioMed research …, 2016 - Wiley Online Library
Due to their permanent and close proximity to neurons, glial cells perform essential tasks for
the normal physiology of the retina. Astrocytes and Müller cells (retinal macroglia) provide …

Conditional Müller cell ablation causes independent neuronal and vascular pathologies in a novel transgenic model

W Shen, M Fruttiger, L Zhu, SH Chung… - Journal of …, 2012 - Soc Neuroscience
Müller cells are the major glia of the retina that serve numerous functions essential to retinal
homeostasis, yet the contribution of Müller glial dysfunction to retinal diseases remains …

Contribution of Müller cells in the diabetic retinopathy development: Focus on oxidative stress and inflammation

R Carpi-Santos, RA de Melo Reis, FCA Gomes… - Antioxidants, 2022 - mdpi.com
Diabetic retinopathy is a neurovascular complication of diabetes and the main cause of
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …

GABA and glutamate uptake and metabolism in retinal glial (Müller) cells

A Bringmann, A Grosche, T Pannicke… - Frontiers in …, 2013 - frontiersin.org
Müller cells, the principal glial cells of the retina, support the synaptic activity by the uptake
and metabolization of extracellular neurotransmitters. Müller cells express uptake and …

Astrocytes and Müller cell alterations during retinal degeneration in a transgenic rat model of retinitis pigmentosa

L Fernández-Sánchez, P Lax, L Campello… - Frontiers in cellular …, 2015 - frontiersin.org
Purpose: Retinitis pigmentosa includes a group of progressive retinal degenerative
diseases that affect the structure and function of photoreceptors. Secondarily to the loss of …