Four homoisoflavonoids named portulacanones A− D, identified as 2′-hydroxy-5, 7-
dimethoxy-3-benzyl-chroman-4-one, 2′-hydroxy-5, 6, 7-trimethoxy-3-benzyl-chroman-4 …

The conversion of CO2 into high value-added chemical products is the focus of current
scientific research. We make use of the specific porous structure of nanosized metal–organic …

Experimental evidence suggests that selective CB2 receptor modulators may provide
access to antihyperalgesic agents devoid of psychotropic effects. Taking advantage of …

In order to determine the regularities of the structure–analgesic activity relationship, the
peculiarities of obtaining, the spatial structure, and biological properties of 4-methyl-2, 2 …

The analysis of our previous studies on the search for synthetic analgesics among NR-
amides of bicyclic hetaryl-3-carboxylic acids has been performed; on its basis N-hetaryl …

Hydrolysis of 1-R-4-hydroxy-2, 2-dioxo-1Н-2λ 6, 1-benzothiazine-3-carboxylate esters in
HCl–AcOH–H 2 O mixture at 60° С was accompanied by decarboxylation and led to 1-R-4 …

Guided by bioisosteric replacement principles, a series of new N-(hetarylmethyl)-4-hydroxy-
6, 7-dimethoxy-2-oxo-1, 2-dihydroquinoline-3-carboxamides were synthesized …

One of the most convenient methods for obtaining ethyl of N-substituted 4-hydroxy-2-oxo-1,
2-dihydroquinoline-3-carboxylates and their tricyclic analogues at present is condensation …

A series of close analogs of 4-hydroxy-6, 7-dimethoxy-2-oxo-N-(pyridin-3-ylmethyl)-1, 2-
dihydroquinoline-3-carboxamide modified in the benzene moiety of the quinolone nucleus …

In numerous studies of 4-hydroxy-2-oxo-1, 2-dihydroquinoline-3-carboxamides it has been
convincingly shown that amidation of quinoline-3-carboxylic acids esters with alkyl-, aryl-and …