Evidence shows that neutrophils can protect the host against pathogens in multiple ways,
including the formation and release of neutrophil extracellular traps (NETs). NETs are web …

Neutrophils are crucial innate immune cells and comprise 50–70% of the white blood cell
population under homeostatic conditions. Upon infection and in cancer, blood neutrophil …

Significance: As a redox-sensitive protein, high-mobility group box 1 (HMGB1) is implicated
in regulating stress responses to oxidative damage and cell death, which are closely related …

Neutrophils are the principal trouper of the innate immune system. Activated neutrophils
undergo a noble cell death termed NETosis and release a mesh-like structure called …

Hepatocellular carcinoma (HCC) is often associated with poor outcomes due to lung
metastasis. ICAM-1+ circulating tumor cells, termed circulating cancer stem cells (CCSCs) …

Recent studies highlight the importance of baseline functional immunity for immune
checkpoint blockade therapies. High‐dimensional systemic immune profiling is performed in …

NETs are chromatin-derived webs extruded from neutrophils as a result of either infection or
sterile stimulation using chemicals, cytokines, or microbes. In addition to the classical role …

Background Thrombotic events cannot be completely prevented by antithrombotics,
implicating a therapeutic gap due to inflammation, a not yet sufficiently addressed …

The process of neutrophil extracellular traps (NETs) formation, called NETosis, is a peculiar
death modality of neutrophils, which was first observed as an immune response against …

Simple Summary Cancer immunotherapies using antibodies and genetically modified T
cells are effective in a subset of cancer patients. However, many cancer patients do not …