Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus
L Cheng, J Wang, H Dai, Y Duan, Y An, L Shi, Y Lv… - Adipocyte, 2021 - Taylor & Francis
Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …
[HTML][HTML] Glial cells shape pathology and repair after spinal cord injury
Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …
correctly surmised that microglia in pathologic central nervous system (CNS) were …
MicroRNAs: roles in regulating neuroinflammation
MicroRNAs (miRNAs) are small noncoding RNAs that broadly affect cellular and
physiological function in all multicellular organisms. Here, the role of miRNAs in …
physiological function in all multicellular organisms. Here, the role of miRNAs in …
Senolytic effects of quercetin in an in vitro model of pre-adipocytes and adipocytes induced senescence
E Zoico, N Nori, E Darra, M Tebon, V Rizzatti… - Scientific reports, 2021 - nature.com
The dysfunction of adipose tissue with aging and the accumulation of senescent cells has
been implicated in the pathophysiology of chronic diseases. Recently interventions capable …
been implicated in the pathophysiology of chronic diseases. Recently interventions capable …
[HTML][HTML] Adipocyte-derived extracellular vesicles regulate survival and function of pancreatic β cells
I Gesmundo, B Pardini, E Gargantini, G Gamba… - JCI insight, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are implicated in the crosstalk between adipocytes and other
metabolic organs, and an altered biological cargo has been observed in EVs from human …
metabolic organs, and an altered biological cargo has been observed in EVs from human …
Adipose tissue fibrosis: mechanisms, models, and importance
Increases in adipocyte volume and tissue mass due to obesity can result in inflammation,
further dysregulation in adipose tissue function, and eventually adipose tissue fibrosis. Like …
further dysregulation in adipose tissue function, and eventually adipose tissue fibrosis. Like …
Regulatory microRNAs in brown, brite and white adipose tissue
MicroRNAs (miRNAs) constitute a class of short noncoding RNAs which regulate gene
expression by targeting messenger RNA, inducing translational repression and messenger …
expression by targeting messenger RNA, inducing translational repression and messenger …
Mechanisms of impaired brown adipose tissue recruitment in obesity
M Alcalá, M Calderon-Dominguez, D Serra… - Frontiers in …, 2019 - frontiersin.org
Brown adipose tissue (BAT) dissipates energy to produce heat. Thus, it has the potential to
regulate body temperature by thermogenesis. For the last decade, BAT has been in the …
regulate body temperature by thermogenesis. For the last decade, BAT has been in the …
Adipocyte, immune cells, and miRNA crosstalk: a novel regulator of metabolic dysfunction and obesity
Obesity is characterized as a complex and multifactorial excess accretion of adipose tissue
(AT) accompanied with alterations in the immune response that affects virtually all age and …
(AT) accompanied with alterations in the immune response that affects virtually all age and …
Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D
E Karkeni, L Bonnet, J Marcotorchino, F Tourniaire… - Epigenetics, 2018 - Taylor & Francis
Inflammation of adipose tissue is believed to be a contributing factor to many chronic
diseases associated with obesity. Vitamin D (VD) is now known to limit this metabolic …
diseases associated with obesity. Vitamin D (VD) is now known to limit this metabolic …