[HTML][HTML] Drug resistant TB–latest developments in epidemiology, diagnostics and management
S Tiberi, N Utjesanovic, J Galvin, R Centis… - International Journal of …, 2022 - Elsevier
Aim The aim of this review is to inform the reader on the latest developments in
epidemiology, diagnostics and management. Epidemiology Drug-resistant Tuberculosis (DR …
epidemiology, diagnostics and management. Epidemiology Drug-resistant Tuberculosis (DR …
[HTML][HTML] Application of next generation sequencing for diagnosis and clinical management of drug-resistant tuberculosis: updates on recent developments in the field
N Dookie, A Khan, N Padayatchi, K Naidoo - Frontiers in Microbiology, 2022 - frontiersin.org
The World Health Organization's End TB Strategy prioritizes universal access to an early
diagnosis and comprehensive drug susceptibility testing (DST) for all individuals with …
diagnosis and comprehensive drug susceptibility testing (DST) for all individuals with …
[HTML][HTML] Bedaquiline- and clofazimine- selected Mycobacterium tuberculosis mutants: further insights on resistance driven largely by Rv0678
J Snobre, MC Villellas, N Coeck, W Mulders… - Scientific Reports, 2023 - nature.com
Drug-resistant tuberculosis is a serious global health threat. Bedaquiline (BDQ) is a
relatively new core drug, targeting the respiratory chain in Mycobacterium tuberculosis (Mtb) …
relatively new core drug, targeting the respiratory chain in Mycobacterium tuberculosis (Mtb) …
Advances in key drug target identification and new drug development for tuberculosis
J Mi, W Gong, X Wu - BioMed Research International, 2022 - Wiley Online Library
Tuberculosis (TB) is a severe infectious disease worldwide. The increasing emergence of
drug‐resistant Mycobacterium tuberculosis (Mtb) has markedly hampered TB control …
drug‐resistant Mycobacterium tuberculosis (Mtb) has markedly hampered TB control …
[HTML][HTML] Clinical utility of target amplicon sequencing test for rapid diagnosis of drug-resistant Mycobacterium tuberculosis from respiratory specimens
KSS Leung, KKG Tam, TTL Ng, HY Lao… - Frontiers in …, 2022 - frontiersin.org
An in-house-developed target amplicon sequencing by next-generation sequencing
technology (TB-NGS) enables simultaneous detection of resistance-related mutations in …
technology (TB-NGS) enables simultaneous detection of resistance-related mutations in …
[HTML][HTML] The recent rapid expansion of multidrug resistant Ural lineage Mycobacterium tuberculosis in Moldova
The projected trajectory of multidrug resistant tuberculosis (MDR-TB) epidemics depends on
the reproductive fitness of circulating strains of MDR M. tuberculosis (Mtb). Previous efforts to …
the reproductive fitness of circulating strains of MDR M. tuberculosis (Mtb). Previous efforts to …
At long last: short, all-oral regimens for multidrug-resistant tuberculosis in the United States
Multidrug-resistant tuberculosis (MDR-TB) has historically required longer treatment
regimens that were associated with higher unfavorable outcomes and side effects rates …
regimens that were associated with higher unfavorable outcomes and side effects rates …
The recent rapid expansion of multidrug resistant strains of Mycobacterium tuberculosis Ural lineage 4.2 in the Republic of Moldova
The projected trajectory of multidrug resistant tuberculosis (MDR-TB) epidemics depends on
the reproductive fitness of circulating strains of MDR M. tuberculosis (Mtb). Previous efforts to …
the reproductive fitness of circulating strains of MDR M. tuberculosis (Mtb). Previous efforts to …
Guiding pragmatic treatment choices for rifampicin-resistant tuberculosis in the absence of second-line drug susceptibility testing
Extract With recent expansion in the use of bedaquiline and limited access to accurate drug
susceptibility testing (DST), we read with concern of examples of the high prevalence of …
susceptibility testing (DST), we read with concern of examples of the high prevalence of …
[HTML][HTML] A Bayesian approach to estimate the probability of resistance to bedaquiline in the presence of a genomic variant
Background Bedaquiline is a core drug for treatment of rifampicin-resistant tuberculosis. Few
genomic variants have been statistically associated with bedaquiline resistance. Alternative …
genomic variants have been statistically associated with bedaquiline resistance. Alternative …