Diabetes mellitus is a common systematic chronic disease amongst dental patients. The
elevated glucose microenvironment can prolong the healing of tooth extraction sockets …

The case of coronavirus disease (COVID-19) has become a global crisis. In addition, more
variants of the virus have been discovered with easier transmission and more harmful …

Background Patients with diabetes have an increased risk of nonunion and delayed union of
fractures. Macrophages have been shown as a key player in diabetic complications …

Introduction Macrophages are central cells in mediating the inflammatory response.
Objective and Methods We evaluated the effect of high glucose conditions on the …

Environmental pollution stands as one of the most critical challenges affecting human
health, with an estimated mortality rate linked to pollution-induced non-communicable …

Macrophages play an important role in the early development of type 1 diabetes (T1D).
Based on the phenotype, macrophages can be classified into pro-inflammatory (M1) and …

Background Pancreatic beta cell dysfunction and activated macrophage infiltration are early
features in type 1 diabetes pathogenesis. A tricarboxylic acid cycle metabolite that can …

The Advanced Glycation End-Products (AGE)/Receptor for AGEs (RAGE) signaling pathway
exacerbates diabetes-mediated vascular calcification (VC) in vascular smooth muscle cells …

Hyperglycemia, a hallmark of diabetes and various metabolic disorders, has profound
implications for immune cell function. The relationship between elevated blood glucose …

Aims The pathogenesis of diabetic peripheral neuropathy (DPN) is complex, and its
treatment is extremely challenging. MicroRNA‐7a‐5p (miR‐7a‐5p) has been widely …