Toward a science of metabolic engineering
JE Bailey - Science, 1991 - science.org
Application of recombinant DNA methods to restructure metabolic networks can improve
production of metabolite and protein products by altering pathway distributions and rates …
production of metabolite and protein products by altering pathway distributions and rates …
Metabolic engineering
J Nielsen - Applied microbiology and biotechnology, 2001 - Springer
Metabolic engineering has developed as a very powerful approach to optimising industrial
fermentation processes through the introduction of directed genetic changes using …
fermentation processes through the introduction of directed genetic changes using …
Inverse metabolic engineering: a strategy for directed genetic engineering of useful phenotypes
JE Bailey, A Sburlati, V Hatzimanikatis… - Biotechnology and …, 1996 - Wiley Online Library
The classical method of metabolic engineering, identifying a rate‐determining step in a
pathway and alleviating the bottleneck by enzyme overexpression, has motivated much …
pathway and alleviating the bottleneck by enzyme overexpression, has motivated much …
Bacterial hemoglobins and flavohemoglobins: versatile proteins and their impact on microbiology and biotechnology
AD Frey, PT Kallio - FEMS microbiology reviews, 2003 - academic.oup.com
In response to oxygen limitation or oxidative and nitrosative stress, bacteria express three
kinds of hemoglobin proteins: truncated hemoglobins (tr Hbs), hemoglobins (Hbs) and …
kinds of hemoglobin proteins: truncated hemoglobins (tr Hbs), hemoglobins (Hbs) and …
[HTML][HTML] Nonvertebrate hemoglobins: structural bases for reactivity
2.3. 1. Ascaris suum hemoglobin 45 2.3. 2. Chironomus thummi thummi erythrocruorin 47
2.3. 3. Lucina pectinata hemoglobin 49 2.3. 4. Aplysia limacina myoglobin 51 2.3. 5. Glycera …
2.3. 3. Lucina pectinata hemoglobin 49 2.3. 4. Aplysia limacina myoglobin 51 2.3. 5. Glycera …
Use of genetically engineered microorganisms (GEMs) for the bioremediation of contaminants
This paper presents a critical review of the literature on the application of genetically
engineered microorganisms (GEMs) in bioremediation. The important aspects of using …
engineered microorganisms (GEMs) in bioremediation. The important aspects of using …
Recent applications of Vitreoscilla hemoglobin technology in bioproduct synthesis and bioremediation
Since its first use in 1990 to enhance production of α-amylase in E. coli, engineering of
heterologous hosts to express the hemoglobin from the bacterium Vitreoscilla (VHb) has …
heterologous hosts to express the hemoglobin from the bacterium Vitreoscilla (VHb) has …
Intracellular expression of Vitreoscilla hemoglobin alters Escherichia coli energy metabolism under oxygen‐limited conditions
PT Kallio, D Jin KIM, PS Tsai… - European Journal of …, 1994 - Wiley Online Library
An earlier stoichiometric analysis of oxygen‐limited metabolism of Escherichia coli
expressing cloned Vitreoscilla hemoglobin (VHb) suggested improved efficiency of ATP …
expressing cloned Vitreoscilla hemoglobin (VHb) suggested improved efficiency of ATP …
Efficacy of supplementation of α-amylase-producing bacterial culture on the performance, nutrient use, and gut morphology of broiler chickens fed a corn-based diet
A trial was conducted to evaluate the efficacy of an Escherichia coli strain producing α-
amylase of Bacillus stearothermophilus on growth performance, nutrient use, and the …
amylase of Bacillus stearothermophilus on growth performance, nutrient use, and the …
[HTML][HTML] Vitreoscilla hemoglobin: intracellular localization and binding to membranes
The obligate aerobic bacterium, Vitreoscilla, synthesizes elevated quantities of a
homodimeric hemoglobin (VHb) under hypoxic growth conditions. Expression of VHb in …
homodimeric hemoglobin (VHb) under hypoxic growth conditions. Expression of VHb in …