Mode of action-based risk assessment of genotoxic carcinogens

A Hartwig, M Arand, B Epe, S Guth, G Jahnke… - Archives of …, 2020 - Springer
The risk assessment of chemical carcinogens is one major task in toxicology. Even though
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …

Antimutagenic compounds and their possible mechanisms of action

K Słoczyńska, B Powroźnik, E Pękala… - Journal of applied …, 2014 - Springer
Mutagenicity refers to the induction of permanent changes in the DNA sequence of an
organism, which may result in a heritable change in the characteristics of living systems …

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: Human and animal health

EFSA Scientific Committee, S More, V Bampidis… - Efsa …, 2021 - Wiley Online Library
The EFSA has updated the Guidance on risk assessment of the application of nanoscience
and nanotechnologies in the food and feed chain, human and animal health. It covers the …

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health

EFSA Scientific Committee - EFSA Journal, 2021 - orbit.dtu.dk
The EFSA has updated the Guidance on risk assessment of the application of nanoscience
and nanotechnologies in the food and feed chain, human and animal health. It covers the …

[HTML][HTML] Toxicological screening

S Parasuraman - Journal of pharmacology & …, 2011 - ncbi.nlm.nih.gov
Toxicity testing of new compounds is essential for drug development process. The
preclinical toxicity testing on various biological systems reveals the species-, organ-and …

Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health

EFSA Scientific Committee, A Hardy, D Benford… - EFSA …, 2018 - Wiley Online Library
Abstract The European Food Safety Authority has produced this Guidance on human and
animal health aspects (Part 1) of the risk assessment of nanoscience and nanotechnology …

Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment

EFSA Scientific Committee - EFSA Journal, 2011 - Wiley Online Library
Abstract The Scientific Committee reviewed the current state‐of‐the‐science on genotoxicity
testing and provided a commentary and recommendations on genotoxicity testing strategies …

Guidance on the risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain

EFSA Scientific Committee - EFSA Journal, 2011 - Wiley Online Library
Abstract The European Food Safety Authority has developed a practical approach for
assessing potential risks arising from applications of nanoscience and nanotechnologies in …

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

LG Hernández, H van Steeg, M Luijten… - … Research/Reviews in …, 2009 - Elsevier
It is well established that cancer is a multi-step process which involves initiation, promotion
and progression. Chemical carcinogens can alter any of these processes to induce their …

A review of the carcinogenic potential of glyphosate by four independent expert panels and comparison to the IARC assessment

GM Williams, M Aardema, J Acquavella… - Critical Reviews in …, 2016 - Taylor & Francis
Abstract The International Agency for Research on Cancer (IARC) published a monograph
in 2015 concluding that glyphosate is “probably carcinogenic to humans”(Group 2A) based …