SINCERITIES: inferring gene regulatory networks from time-stamped single cell transcriptional expression profiles

N Papili Gao, SMM Ud-Dean, O Gandrillon… - …, 2018 - academic.oup.com
Motivation Single cell transcriptional profiling opens up a new avenue in studying the
functional role of cell-to-cell variability in physiological processes. The analysis of single cell …

[HTML][HTML] Effect of imputation on gene network reconstruction from single-cell RNA-seq data

LH Ly, M Vingron - Patterns, 2022 - cell.com
Despite the advances in single-cell transcriptomics, the reconstruction of gene regulatory
networks remains challenging. Both the large amount of zero counts in experimental data …

Network inference with granger causality ensembles on single-cell transcriptomic data

A Deshpande, LF Chu, R Stewart, A Gitter - BioRxiv, 2019 - biorxiv.org
Advances in single-cell transcriptomics enable measuring the gene expression of individual
cells, allowing cells to be ordered by their state in a dynamic biological process. Many …

Analysis of single-cell transcriptional profiles

N Papili Gao - 2019 - research-collection.ethz.ch
Over the last decade, advances in transcriptional profiling technology, such as real-time
PCR (polymerase chain reaction) and RNA-sequencing, have provided researchers with the …