Objective To assess the effect of tranexamic acid on blood transfusion, thromboembolic
events, and mortality in surgical patients. Design Systematic review and meta-analysis. Data …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Background: Total knee arthroplasty is associated with substantial blood loss and the risks
of transfusion. Conflicting reports have been published regarding the effectiveness and …

Background: Topical application of tranexamic acid to bleeding wound surfaces reduces
blood loss in patients undergoing some major surgeries, without systemic complications …

We conducted a systematic review and meta-analysis of randomised controlled trials
evaluating the effect of tranexamic acid (TXA) upon blood loss and transfusion in primary …

We report a systematic review and meta-analysis of published randomised controlled trials
evaluating the efficacy of tranexamic acid (TXA) in reducing blood loss and transfusion in …

Background and purpose Multimodal techniques can aid early rehabilitation and discharge
of patients following primary joint replacement. We hypothesized that this not only reduces …

Background Tranexamic acid (TXA) is an antifibrinolytic drug used as a blood-sparing
technique in many surgical specialties. The principal objective of our meta-analysis was to …

Studies have shown that antifibrinolytic (aprotinin, tranexamic acid, epsilon-aminocaproic
acid) reduce blood loss in orthopedic surgery. However, most lacked sufficient power to …

Background To examine the safety and efficacy of topical use of tranexamic acid (TA) in total
knee arthroplasty (TKA). Methods An electronic literature search of PubMed Medline; Ovid …