Summary The Protein Data Bank (PDB) was established in 1971 to archive three-
dimensional (3D) structures of biological macromolecules as a public good. Fifty years later …

Pfam is a large collection of protein families and domains. Over the past 2 years the number
of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology …

The ability to predict protein function from structure is becoming increasingly important as
the number of structures resolved is growing more rapidly than our capacity to study …

Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RSCB
PDB) provides a wide range of digital data regarding biology and biomedicine. This huge …

CHAINSAW is a model editing program for use in molecular replacement. Given a sequence
alignment between template and target, it modifies the template structure on a residue-by …

Motivation: Recent studies have found many proteins containing regions that do not form
well-defined three-dimensional structures in their native states. The study and detection of …

The Uppsala Electron Density Server (EDS; https://eds. bmc. uu. se/) is a web-based facility
that provides access to electron-density maps and statistics concerning the fit of crystal …

Arginine is an abundant residue in protein–protein interfaces. The importance of this residue
relates to the versatility of its side chain in intermolecular interactions. Different classes of …

Fluorine is the thirteenth most abundant element in the earth's crust, but fluoride
concentrations in surface water are low and fluorinated metabolites are extremely rare,. The …

Background Post-translational phosphorylation is one of the most common protein
modifications. Phosphoserine, threonine and tyrosine residues play critical roles in the …