The origin of animal multicellularity and cell differentiation

T Brunet, N King - Developmental cell, 2017 - cell.com
Over 600 million years ago, animals evolved from a unicellular or colonial organism whose
cell (s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar …

The origin of Metazoa: a unicellular perspective

A Sebé-Pedrós, BM Degnan, I Ruiz-Trillo - Nature Reviews Genetics, 2017 - nature.com
The first animals evolved from an unknown single-celled ancestor in the Precambrian
period. Recently, the identification and characterization of the genomic and cellular traits of …

Early metazoan cell type diversity and the evolution of multicellular gene regulation

A Sebé-Pedrós, E Chomsky, K Pang… - Nature ecology & …, 2018 - nature.com
A hallmark of metazoan evolution is the emergence of genomic mechanisms that implement
cell-type-specific functions. However, the evolution of metazoan cell types and their …

The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition

N Ros-Rocher, A Pérez-Posada, MM Leger… - Open …, 2021 - royalsocietypublishing.org
How animals evolved from a single-celled ancestor, transitioning from a unicellular lifestyle
to a coordinated multicellular entity, remains a fascinating question. Key events in this …

The origin of metazoan multicellularity: a potential microbial black swan event

I Ruiz-Trillo, K Kin, E Casacuberta - Annual Review of …, 2023 - annualreviews.org
The emergence of animals from their unicellular ancestors is a major evolutionary event.
Thanks to the study of diverse close unicellular relatives of animals, we now have a better …

Phylogenomics reveals convergent evolution of lifestyles in close relatives of animals and fungi

G Torruella, A De Mendoza, X Grau-Bové, M Antó… - Current Biology, 2015 - cell.com
The Opisthokonta are a eukaryotic supergroup divided in two main lineages: animals and
related protistan taxa, and fungi and their allies [1, 2]. There is a great diversity of lifestyles …

Origin of animal multicellularity: precursors, causes, consequences—the choanoflagellate/sponge transition, neurogenesis and the Cambrian explosion

T Cavalier-Smith - … Transactions of the Royal Society B …, 2017 - royalsocietypublishing.org
Evolving multicellularity is easy, especially in phototrophs and osmotrophs whose multicells
feed like unicells. Evolving animals was much harder and unique; probably only one …

Regulated aggregative multicellularity in a close unicellular relative of metazoa

A Sebé-Pedrós, M Irimia, J Del Campo, H Parra-Acero… - Elife, 2013 - elifesciences.org
The evolution of metazoans from their unicellular ancestors was one of the most important
events in the history of life. However, the cellular and genetic changes that ultimately led to …

Intestinal morphogenesis in development, regeneration, and disease: the potential utility of intestinal organoids for studying compartmentalization of the crypt-villus …

O Kwon, TS Han, MY Son - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
The morphology and structure of the intestinal epithelium are rearranged dynamically during
development, tissue regeneration, and disease progression. The most important …

Global transcriptome analysis of the aphelid Paraphelidium tribonemae supports the phagotrophic origin of fungi

G Torruella, X Grau-Bové, D Moreira… - Communications …, 2018 - nature.com
Aphelids are little-known phagotrophic parasites of algae whose life cycle and morphology
resemble those of the parasitic rozellids (Cryptomycota, Rozellomycota). In previous …