Molecular mechanisms and physiological importance of circadian rhythms

A Patke, MW Young, S Axelrod - Nature reviews Molecular cell biology, 2020 - nature.com
To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Using FlyAtlas to identify better Drosophila melanogaster models of human disease

VR Chintapalli, J Wang, JAT Dow - Nature genetics, 2007 - nature.com
FlyAtlas, a new online resource, provides the most comprehensive view yet of expression in
multiple tissues of Drosophila melanogaster. Meta-analysis of the data shows that a …

[图书][B] Insect physiology and biochemistry

JL Nation Sr - 2022 - taylorfrancis.com
Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus

RA Akhtar, AB Reddy, ES Maywood, JD Clayton… - Current biology, 2002 - cell.com
Background: Genes encoding the circadian pacemaker in the hypothalamic suprachiasmatic
nuclei (SCN) of mammals have recently been identified, but the molecular basis of circadian …

Molecular genetic analysis of circadian timekeeping in Drosophila

PE Hardin - Advances in genetics, 2011 - Elsevier
A genetic screen for mutants that alter circadian rhythms in Drosophila identified the first
clock gene—the period (per) gene. The per gene is a central player within a transcriptional …

The role of the circadian clock system in physiology

V Pilorz, C Helfrich-Förster, H Oster - Pflügers Archiv-European Journal of …, 2018 - Springer
Life on earth is shaped by the 24-h rotation of our planet around its axes. To adapt behavior
and physiology to the concurring profound but highly predictable changes, endogenous …

The circadian timekeeping system of Drosophila

PE Hardin - Current biology, 2005 - cell.com
Daily rhythms in behavior, physiology and metabolism are controlled by endogenous
circadian clocks. At the heart of these clocks is a circadian oscillator that keeps circadian …

JETLAG Resets the Drosophila Circadian Clock by Promoting Light-Induced Degradation of TIMELESS

K Koh, X Zheng, A Sehgal - Science, 2006 - science.org
Organisms ranging from bacteria to humans synchronize their internal clocks to daily cycles
of light and dark. Photic entrainment of the Drosophila clock is mediated by proteasomal …

Roles of the Two Drosophila CRYPTOCHROME Structural Domains in Circadian Photoreception

A Busza, M Emery-Le, M Rosbash, P Emery - Science, 2004 - science.org
CRYPTOCHROME (CRY) is the primary circadian photoreceptor in Drosophila. We show
that CRY binding to TIMELESS (TIM) is light-dependent in flies and irreversibly commits TIM …

Molecular and phylogenetic analyses reveal mammalian-like clockwork in the honey bee (Apis mellifera) and shed new light on the molecular evolution of the …

EB Rubin, Y Shemesh, M Cohen, S Elgavish… - Genome …, 2006 - genome.cshlp.org
The circadian clock of the honey bee is implicated in ecologically relevant complex
behaviors. These include time sensing, time-compensated sun-compass navigation, and …