Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

COVID-19 has expanded across the world since its discovery in Wuhan (China) and has
had a significant impact on people's lives and health. Long COVID is a term coined by the …

Abstract Objectives One-fifth of Covid-19 patients suffer a severe course of Covid-19
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …

Objectives Hyper-inflammation caused by COVID-19 may be mediated by mast cell
activation (MCA) which has also been hypothesized to cause Long-COVID (LC) symptoms …

SARS-CoV-2 infection is required for COVID-19, but many signs and symptoms of COVID-19
differ from common acute viral diseases. SARS-CoV-2 infection is necessary but not …

Introduction: Fatigue is a common acute symptom following SARS-CoV-2 infection (COVID-
19). The presence of persistent fatigue and impaired daily physical and cognitive function …

Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

Mast cells are derived from hematopoietic stem cell precursors and are essential to the
genesis and manifestations of the allergic response. Activation of these cells by allergens …

Introduction Mast cells are found in all tissues and express numerous surface receptors
allowing them to sense and respond to allergic, autoimmune, environmental …

Orthostatic intolerance and other autonomic dysfunction syndromes are emerging as distinct
symptom clusters in Long Covid. Often accompanying these are common, multi-system …