Mechanisms of angiogenesis in microbe-regulated inflammatory and neoplastic conditions

S Sajib, FT Zahra, MS Lionakis, NA German… - Angiogenesis, 2018 - Springer
Commensal microbiota inhabit all the mucosal surfaces of the human body. It plays
significant roles during homeostatic conditions, and perturbations in numbers and/or …

[HTML][HTML] Role of cyclooxygenase-2 in gastric cancer development and progression

J Cheng, XM Fan - World Journal of Gastroenterology: WJG, 2013 - ncbi.nlm.nih.gov
Although the incidence of gastric cancer has been declining in recent decades, it remains a
major public health issue as the second leading cause of cancer death worldwide. In China …

Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs

WT Steegenga, MV Boekschoten, C Lute, GJ Hooiveld… - Age, 2014 - Springer
Aging is a progressive process that results in the accumulation of intra-and extracellular
alterations that in turn contribute to a reduction in health. Age-related changes in DNA …

[HTML][HTML] A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

WR Coward, CA Feghali-Bostwick, G Jenkins… - The FASEB …, 2014 - ncbi.nlm.nih.gov
Selective silencing of the cyclooxygenase-2 (COX-2) gene with the loss of the antifibrotic
mediator prostaglandin E 2 contributes to the fibrotic process in idiopathic pulmonary fibrosis …

Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation

Z Herceg, MP Lambert, K van Veldhoven… - …, 2013 - academic.oup.com
Remarkable progress in the field of epigenetics has turned academic, medical and public
attention to the potential applications of these new advances in medicine and various fields …

Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse

H Chen, J Li, L Jiao, RB Petersen, J Li… - The Journal of …, 2014 - Wiley Online Library
Key points Diabetic nephropathy (DN) is a major complication of diabetes, key features of
which include glomerular mesangial expansion, hypertrophy, renal inflammation and …

Stepwise cumulation of RUNX3 methylation mediated by Helicobacter pylori infection contributes to gastric carcinoma progression

XX Lu, JL Yu, LS Ying, J Han, S Wang, QM Yu… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Helicobacter pylori has been recognized as a definite carcinogen for
gastric cancer (GC); however, the pathogenesis of H. pylori infection remains unclear. Runt …

Histone deacetylase functions in gastric cancer: therapeutic target?

A Badie, C Gaiddon, G Mellitzer - Cancers, 2022 - mdpi.com
Simple Summary Our knowledge about the identity of many cancers has increased greatly
during the last years and progress in their early identification as well as treatment options …

Hypothetical protein Rv3423.1 of Mycobacterium tuberculosis is a histone acetyltransferase

L Jose, R Ramachandran, R Bhagavat… - The FEBS …, 2016 - Wiley Online Library
We isolated an 8 kDa mycobacterial hypothetical protein, Rv3423. 1, from the chromatin of
human macrophages infected with Mycobacterium tuberculosis H37Rv. Bioinformatics …

The enterochromaffin-like [ECL] cell—Central in gastric physiology and pathology

HL Waldum, ØF Sørdal, PG Mjønes - International Journal of Molecular …, 2019 - mdpi.com
Background: Studies on the regulation of gastric and pancreatic secretion began more than
100 years ago. Secretin was the first hormone postulated to exist, initiating the field of …