Recent studies on the antimicrobial activity of transition metal complexes of groups 6–12

S Nasiri Sovari, F Zobi - Chemistry, 2020 - mdpi.com
Antimicrobial resistance is an increasingly serious threat to global public health that requires
innovative solutions to counteract new resistance mechanisms emerging and spreading …

Ruthenium complexes in the fight against pathogenic microorganisms. An extensive review

AC Munteanu, V Uivarosi - Pharmaceutics, 2021 - mdpi.com
The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …

'Carbon-monoxide-releasing molecule-2 (CORM-2)'is a misnomer: ruthenium toxicity, not CO release, accounts for its antimicrobial effects

HM Southam, MP Williamson, JA Chapman, RL Lyon… - Antioxidants, 2021 - mdpi.com
Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …

Nanotechnology approaches for rapid detection and theranostics of antimicrobial resistant bacterial infections

S Saxena, K Punjabi, N Ahamad, S Singh… - ACS biomaterials …, 2022 - ACS Publications
As declared by WHO, antimicrobial resistance (AMR) is a high priority issue with a pressing
need to develop impactful technologies to curb it. The rampant and inappropriate use of …

Ruthenium‐based Photoactive Metalloantibiotics

A Jain, NT Garrett, ZP Malone - Photochemistry and …, 2022 - Wiley Online Library
Antibiotic resistance is one of the world's most urgent public health problems. Antimicrobial
photodynamic therapy (aPDT) is a promising therapy to combat the growing threat of …

Recent advances on carbon monoxide releasing molecules for antibacterial applications

J Cheng, J Hu - ChemMedChem, 2021 - Wiley Online Library
Carbon monoxide (CO) has been known as an endogenous signaling molecule in addition
to an air pollutant. It plays a critical role in many physiological and pathological processes …

Ruthenium based antimicrobial theranostics–using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus

KL Smitten, SD Fairbanks, CC Robertson… - Chemical …, 2020 - pubs.rsc.org
In previous studies we reported that specific dinuclear RuII complexes are particularly active
against pathogenic Gram-negative bacteria and, unusually for this class of compounds …

Mononuclear ruthenium (ii) theranostic complexes that function as broad-spectrum antimicrobials in therapeutically resistant pathogens through interaction with DNA

KL Smitten, EJ Thick, HM Southam, JB de la Serna… - Chemical …, 2020 - pubs.rsc.org
Six luminescent, mononuclear ruthenium (II) complexes based on the tetrapyridophenazine
(tpphz) and dipyridophenazine (dppz) ligands are reported. The therapeutic activities of the …

Anti-bacterial, anti-biofilm and synergistic effects of phenazine-based ruthenium (II) complexes

PHR Martins, AIB Romo, FS Gouveia Jr, IA Paz… - Dalton …, 2024 - pubs.rsc.org
Antimicrobial resistance has become a global threat to human health, which is coupled with
the lack of novel drugs. Metallocompounds have emerged as promising diverse scaffolds for …

Synthesis, Characterisation and Antimicrobial Studies of some 2,6‐bis(1,2,3‐Triazol‐4‐yl)Pyridine Ruthenium(II) “Click” Complexes

QVC van Hilst, RAS Vasdev, D Preston… - Asian Journal of …, 2019 - Wiley Online Library
A family of homo‐and hetero‐leptic ruthenium (II) bis‐tridentate complexes generated from
2, 6‐bis (1‐R‐1, 2, 3‐triazol‐4‐yl) pyridine “click” ligands (R‐tripy) with either aliphatic or …