AMP-activated protein kinase (AMPK), a member of the serine/threonine (Ser/Thr) kinase
group, is universally distributed in various cells and organs. It is a significant endogenous …

Stroke remains a leading cause of adult motor disabilities in the world and accounts for the
greatest number of hospitalizations for neurological disease. Stroke treatments/therapies …

Regular exercise promotes whole-body health and prevents disease, but the underlying
molecular mechanisms are incompletely understood,–. Here, the Molecular Transducers of …

Exercise preconditioning has attracted extensive attention to induce endogenous
neuroprotection and has become the hotspot in neurotherapy. The training exercise is given …

There remain debates on neuroprotection and rehabilitation techniques for acute ischemic
stroke patients. Therapeutic physical exercise following stroke has shown promise but is …

Stroke remains a significant unmet clinical need with limited therapeutic options. The
peculiar feature of ischemic stroke is the interruption in brain circulation, resulting in a …

Objective: Preconditioning exercise can exert neuroprotective effects after stroke; however,
the effects of exercise intensity, frequency, duration are unknown. We investigated the …

Physical exercise is an effective therapy for neurorehabilitation. Exercise has been shown to
induce remodeling and proliferation of astrocyte. Astrocytes potentially affect the recruitment …

Stroke remains a significant unmet need in the clinic with few therapeutic options. We, and
others, have implicated the role of inflammatory microbiota in stroke secondary cell death …

Regular exercise promotes whole-body health and prevents disease, yet the underlying
molecular mechanisms throughout a whole organism are incompletely understood. Here …