Early physical rehabilitation in intensive care patients with sepsis syndromes: a pilot randomised controlled trial

G Kayambu, R Boots, J Paratz - Intensive care medicine, 2015 - Springer
Rationale Survivors of sepsis syndromes have poor outcomes for physical and cognitive
function. No investigations of early physical rehabilitation in the intensive care unit have …

Physical exercise as a friend not a foe in acute kidney diseases through immune system modulation

AC Costanti-Nascimento, L Brelaz-Abreu… - Frontiers in …, 2023 - frontiersin.org
Regular and moderate exercise is being used for therapeutic purposes in treating several
diseases, including cancer, cardiovascular diseases, arthritis, and even chronic kidney …

Non-invasive pulsatile shear stress modifies endothelial activation; a narrative review

JA Adams, A Uryash, JR Lopez - Biomedicines, 2022 - mdpi.com
The monolayer of cells that line both the heart and the entire vasculature is the endothelial
cell (EC). These cells respond to external and internal signals, producing a wide array of …

Aerobic exercise improves LPS-induced sepsis via regulating the Warburg effect in mice

X Wang, Z Wang, D Tang - Scientific reports, 2021 - nature.com
We investigated the impact of aerobic exercise (AE) on multiple organ dysfunction syndrome
(MODS), aortic injury, pathoglycemia, and death during sepsis. ICR mice were randomized …

Moderate exercise-induced dynamics on key sepsis-associated signaling pathways in the liver

HP Osuru, K Ikeda, N Atluri, RH Thiele - Critical Care, 2023 - Springer
Background There is a clear relationship between quantitative measures of fitness (eg, VO2
max) and outcomes after surgical procedures. Whether or not fitness is a modifiable risk …

Temporal dynamics of the multi-omic response to endurance exercise training across tissues

MoTrPAC Study Group, D Amar, NR Gay… - BioRxiv, 2022 - biorxiv.org
Regular exercise promotes whole-body health and prevents disease, yet the underlying
molecular mechanisms throughout a whole organism are incompletely understood. Here …

Bakuchiol from Psoralea corylifolia L. Ameliorates acute kidney injury and improves survival in experimental polymicrobial sepsis

J Wang, M Luo, J Shen, Z Liu, Y Chen, J Luo… - International …, 2020 - Elsevier
Bakuchiol (BAK) is a prenylated phenolic mono-terpene extracted from the fruit of Psoralea
corylifolia L., which exerts a protective effect on organs. However, whether BAK has a …

Phospholipid screening postcardiac arrest detects decreased plasma lysophosphatidylcholine: supplementation as a new therapeutic approach

M Nishikimi, T Yagi, M Shoaib, R Takegawa… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: Cardiac arrest and subsequent resuscitation have been shown to deplete
plasma phospholipids. This depletion of phospholipids in circulating plasma may contribute …

Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice

K Tyml, S Swarbreck, C Pape, D Secor, J Koropatnick… - Critical Care, 2017 - Springer
Background Despite many animal studies and clinical trials, mortality in sepsis remains high.
This may be due to the fact that most experimental studies of sepsis employ young animals …

Exercise training modifies gut microbiota with attenuated host responses to sepsis in wild‐type mice

D Kim, H Kang - The FASEB Journal, 2019 - Wiley Online Library
This study investigated the effects of exercise preconditioning‐induced modification in gut
microbiota composition and host responses to cecal ligation and puncture (CLP)‐induced …