The choroid plexus: a missing link in our understanding of brain development and function

NR Saunders, KM Dziegielewska… - Physiological …, 2023 - journals.physiology.org
Studies of the choroid plexus lag behind those of the more widely known blood-brain barrier,
despite a much longer history. This review has two overall aims. The first is to outline long …

Maternal metabolism influences neural tube closure

RA Keuls, RH Finnell, RJ Parchem - Trends in Endocrinology & Metabolism, 2023 - cell.com
Changes in maternal nutrient availability due to diet or disease significantly increase the risk
of neural tube defects (NTDs). Because the incidence of metabolic disease continues to rise …

[HTML][HTML] Neural crest metabolism: At the crossroads of development and disease

D Bhattacharya, B Khan, M Simoes-Costa - Developmental biology, 2021 - Elsevier
The neural crest is a migratory stem cell population that contributes to various tissues and
organs during vertebrate embryonic development. These cells possess remarkable …

Mitochondria in early forebrain development: from neurulation to mid-corticogenesis

RM Fame, MK Lehtinen - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Function of the mature central nervous system (CNS) requires a substantial proportion of the
body's energy consumption. During development, the CNS anlage must maintain its …

Micronutrient imbalance and common phenotypes in neural tube defects

AD Kakebeen, L Niswander - genesis, 2021 - Wiley Online Library
Neural tube defects (NTDs) are among the most common birth defects, with a prevalence of
close to 19 per 10,000 births worldwide. The etiology of NTDs is complex involving the …

Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model

A Horánszky, B Shashikadze, R Elkhateib… - Frontiers in Cell and …, 2023 - frontiersin.org
Bisphenol A (BPA) exposure is associated with a plethora of neurodevelopmental
abnormalities and brain disorders. Previous studies have demonstrated BPA-induced …

The miR‐302/367 cluster: Aging, inflammation, and cancer

Z Li, Y Duan, S Yan, Y Zhang… - Cell Biochemistry and …, 2023 - Wiley Online Library
MicroRNAs (miRNAs) are a class of noncoding RNAs that occupy a significant role in
biological processes as important regulators of intracellular homeostasis. First, we will …

Glycolytic activity is required for the onset of neural plate folding during neural tube closure in mouse embryos

D Sakai, Y Murakami, D Shigeta… - Frontiers in Cell and …, 2023 - frontiersin.org
Physiological hypoxia is critical for placental mammalian development. However, the
underlying mechanisms by which hypoxia regulates embryonic development remain …

Notes from the 2022 Folate, Vitamin B12, and One-Carbon Metabolism Conference

AG Maynard, B Petrova, N Kanarek - 2023 - mdpi.com
Here, we present notes from the Folate, Vitamin B12, and One-Carbon Metabolism
Conference organized by The Federation of American Societies for Experimental Biology …

Mitochondria in the Central Nervous System in Health and Disease: The Puzzle of the Therapeutic Potential of Mitochondrial Transplantation

K Tripathi, D Ben-Shachar - Cells, 2024 - mdpi.com
Mitochondria, the energy suppliers of the cells, play a central role in a variety of cellular
processes essential for survival or leading to cell death. Consequently, mitochondrial …