[HTML][HTML] Nanoparticle protein corona: from structure and function to therapeutic targeting

G Bashiri, MS Padilla, KL Swingle, SJ Shepherd… - Lab on a Chip, 2023 - pubs.rsc.org
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

The Janus of Protein Corona on nanoparticles for tumor targeting, immunotherapy and diagnosis

X Wang, W Zhang - Journal of Controlled Release, 2022 - Elsevier
The therapeutics based on nanoparticles (NPs) are considered as the promising strategy for
tumor detection and treatment. However, one of the most challenges is the adsorption of …

Engineering at the nano-bio interface: harnessing the protein corona towards nanoparticle design and function

RL Pinals, L Chio, F Ledesma, MP Landry - Analyst, 2020 - pubs.rsc.org
Unpredictable and uncontrollable protein adsorption on nanoparticles remains a
considerable challenge to achieving effective application of nanotechnologies within …

[HTML][HTML] Radioiodination of extravesicular surface constituents to study the biocorona, cell trafficking and storage stability of extracellular vesicles

SS Yerneni, T Solomon, J Smith… - Biochimica et Biophysica …, 2022 - Elsevier
Abstract Background Extracellular vesicles (EVs) are produced by all cell types and serve as
biological packets delivering a wide variety of molecules for cell-to-cell communication …

Peptide-targeted high-density lipoprotein nanoparticles for combinatorial treatment against metastatic breast cancer

C Jiang, X Wang, B Teng, Z Wang, F Li… - … applied materials & …, 2021 - ACS Publications
The sonic hedgehog (SHH) signaling pathway exhibits aberrant activation in triple-negative
breast cancer (TNBC), wherein it regulates several malignant phenotypes related to tumor …

Formation and biological effects of protein corona for food‐related nanoparticles

G Cui, W Su, M Tan - … Reviews in Food Science and Food …, 2022 - Wiley Online Library
The rapid development of nanoscience and nanoengineering provides new perspectives on
the composition of food materials, and has great potential for food biology research and …

How corona formation impacts nanomaterials as drug carriers

MN Gupta, I Roy - Molecular Pharmaceutics, 2020 - ACS Publications
As drugs/drug carriers, upon encountering physiological fluids, nanoparticles adsorb
biological molecules almost immediately to form a biocorona, which is often simply called a …

Deciphering protein corona by scFv-based affinity chromatography

Y Chu, W Tang, Z Zhang, C Li, J Qian, X Wei, T Ying… - Nano Letters, 2021 - ACS Publications
It remains challenging to precisely decipher the structural and functional characteristics of
protein coronas. To overcome the drawbacks frequently occurring in the traditional …

Formation of protein corona on interaction of pepsin with chitin nanowhiskers in simulated gastric fluid

Y Wang, L Zhou, Y Sun, H Mu, X Li, Y Wang, Q Sun - Food Chemistry, 2022 - Elsevier
Protein corona (PC) usually changes the physicochemical properties of nanoparticles (NPs)
and determines their ultimate fate in the physiological environment. As NPs are widely used …

[HTML][HTML] Structural changes in selected human proteins induced by exposure to quantum dots, their biological relevance and possible biomedical applications

D Kunachowicz, M Ściskalska, M Jakubek, R Kizek… - NanoImpact, 2022 - Elsevier
Quantum dots (QDs) are semi-conductor luminescent nanocrystals usually of 2–10 nm
diameter, attracting the significant attention in biomedical studies since emerged. Due to …