Immune regulation by parasites is a global concept that includes suppression, diversion,
and conversion of the host immune response to the benefit of the pathogen. While many …

Insect chitinases belong to family 18 glycosylhydrolases that hydrolyze chitin by an endo-
type of cleavage while retaining the anomeric β-(1→ 4) configuration of products. There are …

In a search of new bone proteins, the glycoprotein YKL-40 was identified in 1989 to be
secreted in vitro in large amount by the human osteosarcoma cell line MG63. The protein …

Abstract Glycoside hydrolase family 18 (GH18) chitinases, which catalyze the
biodegradation of β-1, 4 glycosidic bond in amino polysaccharides via a substrate-assisted …

Abstract Background Chitinases (EC. 3.2. 1.14) hydrolyze the β-1, 4-linkages in chitin, an
abundant N-acetyl-β-D-glucosamine polysaccharide that is a structural component of …

The human cartilage glycoprotein-39 (HCgp-39 or YKL40) is expressed by synovial cells
and macrophages during inflammation. Its precise physiological role is unknown. However …

Expression of the chitinase 3-like protein HC-gp39 (human cartilage glycoprotein 39) is
associated with conditions of increased matrix turnover and tissue remodelling. High levels …

Publisher Summary This chapter highlights some of the recent and important findings
obtained from studies conducted on the synthesis, structure, physical state, modification …

Chitinases are important enzymes required for chitin degradation and reconstruction in
insects. Based on a bioinformatics investigation, we identified 12 genes encoding putative …

Background Chitinases are prevalent in life and are found in species including archaea,
bacteria, fungi, plants, and animals. They break down chitin, which is the second most …