Proteases are excellent biomarkers for a variety of diseases, offer multiple opportunities for
diagnostic applications and are valuable targets for therapy. From a chemistry-based …

Nowadays, it is still quite challenging to achieve an early diagnosis of the Alzheimer disease
(AD) in clinics. The burgeoning near-infrared fluorescence (NIRF) imaging fulfills the …

Delivery of functional proteins into the intracellular space has been a challenging task that
could lead to a myriad of therapeutic applications. We report herein a novel bioconjugation …

The advance of cancer imaging requires innovations to establish novel fluorescent scaffolds
that are excitable and emit in the near-infrared region with favorable Stokes shifts …

Abstract Hydrogen peroxide (H 2 O 2), as one kind of the most significant reactive oxygen
species (ROS), is associated with many physiological and pathological processes in …

Photodynamic therapy is an alternative modality for the therapy of diseases such as cancer
in a minimally invasive manner. The essential photosensitizer, which acts as a catalyst when …

Controlling the packing arrangements of dyes is a facile way of tuning their photophysical
and/or photochemical properties, thus enabling new sensing mechanisms for …

Photodynamic therapy (PDT) is a promising approach for the treatment of different kinds of
cancers as well as some other diseases. By combining spatiotemporal light irradiation with …

Biothiols, such as glutathione (GSH), homocysteine (Hcy) and cysteine (Cys), are important
biomarkers and play crucial roles in many physiological processes. Thus, the detection of …

Activity-based sensing (ABS) offers a general approach that exploits chemical reactivity as a
method for selective detection and manipulation of biological analytes. Here, we illustrate …