As tooth loss is the high end of periodontal problems and edentulous individuals are at
higher risk of nutritional problems like obesity, understanding the association between tooth …

Cardiovascular disease (CVD) is a group of diseases that primarily affect the heart or blood
vessels, with high disability and mortality rates, posing a serious threat to human health. The …

This Special Issue,“Molecular Research on Pulmonary Hypertension 3.0”, of the
International Journal of Molecular Sciences (IJMS) contains seven original research papers …

The multi-ligand receptor for advanced glycation end-products (RAGE) and its ligands are
contributing factors in autoimmunity, cancers, and infectious disease. RAGE activation is …

Dilatation of the aorta is a constantly evolving condition that can lead to the ultimate life-
threatening event, acute aortic dissection. Recent research has tried to identify quantifiable …

Objectives: Interleukin-7 (IL-7) secures B cell maturation, regulatory T and natural killer (NK)
cell survival, and homeostasis, all of which are important for beneficial immunomodulation in …

The number of individuals with diabetes worldwide has quadrupled since 1980, making
diabetes the 4th most common cause of death from non-communicable disease. Since …

Systemic sclerosis (SSc) is a very heterogeneous disease; every patient with SSc is unique,
with variable presentation of clinical features. Furthermore, the disease can show variable …

Introduction Pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD) are the
leading causes of death in systemic sclerosis (SSc). Until now, no prospective biomarker to …

Methods: One hundred eighty-eight SSc patients were followed retrospectively for the
development of ILD, PAH, and mortality for 8 years. Levels of sRAGE and HMGB1 were …