Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …

Dihydropyrimidinones are heterocycles with a pyrimidine moiety in the ring nucleus, which,
in recent decades, have aroused interest in medicinal chemistry due to alleged versatile …

Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3, 4-
dihydropyrimidin-2 (1H)-ones/thiones (DHPMs) have emerged as prototypes for the design …

The present work describes the synthesis, characterization, and application of a new ion‐
tagged iron catalyst. The catalyst was employed in the Biginelli reaction with impressive …

Bronsted and Lewis acid catalysts with ionic tags under homogeneous and heterogeneous
conditions have been tested to perform the Biginelli synthesis of 3, 4-dihydropyrimidin-2 (1 …

This paper describes the synthesis and evaluation of new dihydropyrimidinone (DHPM)-
derived selenoesters as potential multi-targeted agents for the treatment of Alzheimer's …

A series of dihydropyrimidine (DHPM) derivatives bearing 1, 3, 4-oxadiazole moiety was
designed and synthesized as monastrol analogues. The new compounds were screened for …

We described the first synthesis of fatty acid 3, 4-dihydropyrimidinones (DHPM-fatty acids)
using the Biginelli multicomponent reaction. Antiproliferative activity on two glioma cell lines …

An efficient method for the synthesis of quinolines using microwave irradiation was
developed providing 28 quinolines with good yields. The reaction procedures are …

Novel pyrimidinic selenoureas were synthesized and evaluated against tumour and normal
cell lines. Among these, the compound named 3j initially showed relevant cytotoxicity and …