Prescription rates of second-generation antipsychotics (SGAs) are rapidly increasing for non-
indicated (ie, off-label) usage. SGAs used for approved indications are associated with …

Objectives We develop a model for predicting quetiapine levels in patients with depression,
using machine learning to support decisions on clinical regimens. Methods Inpatients …

The atypical antipsychotic drugs, quetiapine and clozapine, are associated with idiosyncratic
drug reactions (such as agranulocytosis or neutropenia) that are thought to involve reactive …

Objective Quetiapine use at standard doses has been associated with hyperglycemia and
dyslipidemia. However, whether even frequently prescribed low‐dose quetiapine results in …

Aim To describe trends in and characteristics of sedative drug use from 2000 through 2019
in relation to the introduction of central regulations and new drugs. Methods In this …

The second‐generation antipsychotic quetiapine is commonly used off‐label for its anxiolytic
and hypnotic properties. However, quetiapine is associated with problematic side‐effects …

Introduction Quetiapine exhibits notable pharmacokinetic and pharmacodynamic (PK/PD)
variability, the origins of which are poorly understood. This systematic review summarizes …

Unspecific symptoms of anxiety and distress are frequently encountered in patients in both
general practice and acute psychiatric services. Minor tranquillizers may be a treatment …

Introduction Patients with severe mental illness (SMI) have a high risk for diabetes,
dyslipidemia, and other components of metabolic syndrome. Patients with these metabolic …

Objective Increasing number of people have been prescribed antipsychotics (APs) off‐label
in recent decades. This study aimed to identify the characteristics and predictors of receiving …