Targeting signaling pathways in prostate cancer: mechanisms and clinical trials
Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …
genomic landscapes and biological functions, the treatment of PCa continues to improve …
Current use of PSMA–PET in prostate cancer management
T Maurer, M Eiber, M Schwaiger… - Nature Reviews …, 2016 - nature.com
Currently, the findings of imaging procedures used for detection or staging of prostate
cancer depend on morphology of lymph nodes or bone metabolism and do not always meet …
cancer depend on morphology of lymph nodes or bone metabolism and do not always meet …
Detection efficacy of 18F-PSMA-1007 PET/CT in 251 patients with biochemical recurrence of prostate cancer after radical prostatectomy
FL Giesel, K Knorr, F Spohn, L Will… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA)–targeted PET imaging recently emerged as a
new method for the staging and restaging of prostate cancer. Most published studies …
new method for the staging and restaging of prostate cancer. Most published studies …
F-18 labelled PSMA-1007: biodistribution, radiation dosimetry and histopathological validation of tumor lesions in prostate cancer patients
FL Giesel, B Hadaschik, J Cardinale, J Radtke… - European journal of …, 2017 - Springer
Purpose The prostate-specific membrane antigen (PSMA) targeted positron-emitting-
tomography (PET) tracer 68 Ga-PSMA-11 shows great promise in the detection of prostate …
tomography (PET) tracer 68 Ga-PSMA-11 shows great promise in the detection of prostate …
PSMA PET/CT: joint EANM procedure guideline/SNMMI procedure standard for prostate cancer imaging 2.0
WP Fendler, M Eiber, M Beheshti, J Bomanji… - European journal of …, 2023 - Springer
Here we aim to provide updated guidance and standards for the indication, acquisition, and
interpretation of PSMA PET/CT for prostate cancer imaging. Procedures and characteristics …
interpretation of PSMA PET/CT for prostate cancer imaging. Procedures and characteristics …
Principles in the design of ligand-targeted cancer therapeutics and imaging agents
M Srinivasarao, CV Galliford, PS Low - Nature reviews Drug discovery, 2015 - nature.com
Most cancer drugs are designed to interfere with one or more events in cell proliferation or
survival. As healthy cells may also need to proliferate and avoid apoptosis, anticancer …
survival. As healthy cells may also need to proliferate and avoid apoptosis, anticancer …
68Ga-and 177Lu-labeled PSMA I&T: optimization of a PSMA-targeted theranostic concept and first proof-of-concept human studies
M Weineisen, M Schottelius, J Simecek… - Journal of Nuclear …, 2015 - Soc Nuclear Med
On the basis of the high and consistent expression of prostate-specific membrane antigen
(PSMA) in metastatic prostate cancer (PC), the goal of this study was the development …
(PSMA) in metastatic prostate cancer (PC), the goal of this study was the development …
Initial Evaluation of [18F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer
Purpose Prostate-specific membrane antigen (PSMA) is a recognized target for imaging
prostate cancer. Here we present initial safety, biodistribution, and radiation dosimetry …
prostate cancer. Here we present initial safety, biodistribution, and radiation dosimetry …
The theranostic PSMA ligand PSMA-617 in the diagnosis of prostate cancer by PET/CT: biodistribution in humans, radiation dosimetry, and first evaluation of tumor …
A Afshar-Oromieh, H Hetzheim… - Journal of Nuclear …, 2015 - Soc Nuclear Med
PET imaging with the prostate-specific membrane antigen (PSMA)–targeted radioligand
68Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer …
68Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer …
Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging
S Sheikhbahaei, A Afshar-Oromieh, M Eiber… - European journal of …, 2017 - Springer
Background The rapidly expanding clinical adaptation of prostate-specific membrane
antigen (PSMA)-targeted PET imaging in the evaluation of patients with prostate cancer has …
antigen (PSMA)-targeted PET imaging in the evaluation of patients with prostate cancer has …