Modulators of the Hop-HSP90 Protein–Protein Interaction Disrupt KSHV Lytic Replication
MO Okpara, MC Vaaltyn, JL Watson… - ACS Infectious …, 2024 - ACS Publications
The central role of the chaperome in maintaining cellular proteostasis has seen numerous
viral families evolve to parasitically exploit host chaperones in their life cycle. The HSP90 …
viral families evolve to parasitically exploit host chaperones in their life cycle. The HSP90 …
[HTML][HTML] Global, regional, and national burden of early-onset gastric cancer
N Tan, H Wu, M Cao, F Yang, X Yan… - Cancer Biology & …, 2024 - pmc.ncbi.nlm.nih.gov
Objective: The burden of gastric cancer (GC) across different age groups needs updating.
We determined the GC global, regional, and national burden profiles and changes in …
We determined the GC global, regional, and national burden profiles and changes in …
Cancer and HIV: The Molecular Mechanisms of the Deadly Duo
A Omar, N Marques, N Crawford - Cancers, 2024 - mdpi.com
Simple Summary Following infection with HIV, individuals are immunocompromised. Their
weakened immune system puts them at a higher risk of certain cancers like Kaposi sarcoma …
weakened immune system puts them at a higher risk of certain cancers like Kaposi sarcoma …
Rapid, equipment-free extraction of DNA from skin biopsies for point-of-care diagnostics
Kaposi's sarcoma (KS) is a cancer affecting skin and internal organs for which the Kaposi's
sarcoma associated herpesvirus (KSHV) is a necessary cause. Previous work has pursued …
sarcoma associated herpesvirus (KSHV) is a necessary cause. Previous work has pursued …
[HTML][HTML] The 'Oma's of the Gammas—Cancerogenesis by γ-Herpesviruses
A Banerjee, D Dass, S Mukherjee, M Kaul… - Viruses, 2024 - mdpi.com
Epstein–Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), which are
the only members of the gamma (γ) herpesviruses, are oncogenic viruses that significantly …
the only members of the gamma (γ) herpesviruses, are oncogenic viruses that significantly …
Global trends in Kaposi sarcoma incidence and mortality: the need for action to reduce inequalities
C Carrilho, N Lunet - The Lancet Global Health, 2023 - thelancet.com
Kaposi sarcoma is a malignant vascular neoplasia that develops into skin lesions, it can
involve one or multiple internal organs, and it is classified as an AIDS-defining cancer. Four …
involve one or multiple internal organs, and it is classified as an AIDS-defining cancer. Four …
Wilms' tumor 1 (WT1) antigen is overexpressed in Kaposi Sarcoma and is regulated by KSHV vFLIP
AE Morales, R Gumenick, CM Genovese… - Plos …, 2024 - journals.plos.org
In people living with HIV, Kaposi Sarcoma (KS), a vascular neoplasm caused by KS
herpesvirus (KSHV/HHV-8), remains one of the most common malignancies worldwide …
herpesvirus (KSHV/HHV-8), remains one of the most common malignancies worldwide …
[PDF][PDF] Pathology of HIV/AIDS
EC Klatt - The Mercer University of Medicine Savannah, 2017 - webpath.med.utah.edu
The human immunodeficiency virus (HIV) was unknown until the early 1980's when
increasing numbers of cases of unusual opportunistic infections and Kaposi sarcoma in …
increasing numbers of cases of unusual opportunistic infections and Kaposi sarcoma in …
Modulators of the Hop-HSP90 Protein-Protein Interaction Disrupt Early-Stage of KSHV Lytic Replication
The central role of the chaperome in maintaining cellular proteostasis has seen numerous
viral families evolve to parasitically exploit host chaperones in their life cycle. The HSP90 …
viral families evolve to parasitically exploit host chaperones in their life cycle. The HSP90 …
A role of BPTF in viral oncogenicity delineated through studies of heritable Kaposi sarcoma
Y Yogev, M Schaffer, M Shlapobersky… - Journal of Medical …, 2024 - Wiley Online Library
Kaposi sarcoma (KS), caused by Herpesvirus‐8 (HHV‐8; KSHV), shows sporadic, endemic,
and epidemic forms. While familial clustering of KS was previously recorded, the molecular …
and epidemic forms. While familial clustering of KS was previously recorded, the molecular …