Acetaminophen (APAP) toxicity is the most common cause of acute liver failure and a major
indication for liver transplantion in the United States and Europe. Although significant …

There are hundreds of central nervous system (CNS) diseases, but there are few diseases
for which the etiology or pathogenesis is understood as well as those of other organ-specific …

Introduction Lorlatinib is a third-generation tyrosine kinase inhibitor approved for the
treatment of anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung …

The nanocarrier-based delivery system has emerged as a promising candidate for cancer
therapy; nevertheless, their quality problems, variation between batches, and carrier-related …

The review begins with molecular genetics, which hit the field unveiling the involvement of
oncogenes and tumor suppressor genes in the pathogenesis of colorectal cancer (CRC) …

Multiple toxic exposures are increasing nowadays. In cases of acute poisoning involving
multiple agents, there is a potential for additional toxicity that goes beyond the effects and …

Conclusions: The syndrome prognosis is related to the stage of the syndrome and the
rapidity and the adequateness of intensive care treatments. The analysis of the patients …

Pediatric acute liver failure (PALF) is a life-threatening disorder characterized by acute
hepatocellular injury occurring in children without recognized underlying liver disease. The …

Aging is a biological process with effects at the molecular, cellular, tissue, organ, system,
and organismal levels and is characterized by decline in physical function and higher risks …

In the 21 st century, the determination of alert thresholds remains the most challenging and
controversial issue in clinical pediatrics. Pre-analytical, analytical, and post-analytical …