Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Reactive oxygen species (ROS) are capable of inducing cell death or apoptosis. Recently,
we demonstrated that lipid-ROS can mediate ferroptosis and activation of human platelets …

Hemolysis, a process by which the destruction of red blood cells leads to the release of
hemoglobin, is a critical event observed during hemolytic disorders. Under oxidative stress …

Hemolytic disease in grass carp (C. idella) leads to hemolysis in vivo, releasing damage-
related molecular patterns (DAMPs) hemoglobin (Hb; which is rapidly oxidized to Hb-Fe3+ …

Background Germinal matrix intraventricular hemorrhage (GM-IVH) is associated with
deposition of redox active cell-free hemoglobin (Hb), derived from hemorrhagic …

The rapid escalation of pandemic health threats associated with the novel, pathogenic
SARS-CoV-2 coronavirus poses unprecedented challenges as proven effective vaccines …

Platelets are anucleate cells, known for their pivotal roles in hemostasis, inflammation,
immunity, and disease progression. Being anuclear, platelets are known to express several …

Human platelets (PLTs) are vulnerable to unfavorable conditions, and their adequate supply
is limited by strict transportation conditions. We report here that PLTs preserved under three …

Envenomation by the Hypnale hypnale in the Western Ghats of India (particularly in the
Malabar region of Kerala) and the subcontinent island nation of Sri Lanka is known to inflict …

Background The oxidative stress environment of pathological tissue has an adverse effect
on the survival of bone marrow mesenchymal stem cells (BMSCs) transplantation. Ginkgo …